Entity Details

Primary name ARRC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP36575
EntryNameARRC_HUMAN
FullNameArrestin-C
TaxID9606
Evidenceevidence at protein level
Length388
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesARR3

GO terms

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GOName
GO:0001664 G protein-coupled receptor binding
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0001932 regulation of protein phosphorylation
GO:0002031 G protein-coupled receptor internalization
GO:0002046 opsin binding
GO:0005737 cytoplasm
GO:0007165 signal transduction
GO:0007601 visual perception
GO:0045202 synapse
GO:0051219 phosphoprotein binding

Subcellular Location

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Subcellular Location
Cell projection
Photoreceptor inner segment

Domains

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DomainNameCategoryType
IPR000698 ArrestinFamilyFamily
IPR011021 Arrestin-like, N-terminalDomainDomain
IPR011022 Arrestin C-terminal-like domainDomainDomain
IPR014752 Arrestin-like, C-terminalFamilyHomologous superfamily
IPR014753 Arrestin, N-terminalFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR017864 Arrestin, conserved siteSiteConserved site
IPR033042 Arrestin-CFamilyFamily

Diseases

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Disease IDSourceNameDescription
301010 OMIMMyopia 26, X-linked, female-limited (MYP26)A form of myopia, a refractive error of the eye, in which parallel rays from a distant object come to focus in front of the retina, vision being better for near objects than for far. MYP26 is characterized by typical tigroid fundus changes commonly seen in early onset high myopia, and an unusual pattern of X-linked female-limited inheritance. The disease may be caused by variants affecting the gene represented in this entry.