Entity Details
| Primary name |
HUTH_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | P42357 |
| EntryName | HUTH_HUMAN |
| FullName | Histidine ammonia-lyase |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 657 |
| SequenceStatus | complete |
| DateCreated | 1995-11-01 |
| DateModified | 2021-06-02 |
Subcellular Location
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Domains
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| Domain | Name | Category | Type |
| IPR001106 | Aromatic amino acid lyase | Family | Family |
| IPR005921 | Histidine ammonia-lyase | Family | Family |
| IPR008948 | L-Aspartase-like | Family | Homologous superfamily |
| IPR021922 | Par3/HAL, N-terminal | Domain | Domain |
| IPR022313 | Phenylalanine/histidine ammonia-lyases, active site | Site | Active site |
| IPR024083 | Fumarase/histidase, N-terminal | Family | Homologous superfamily |
Diseases
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| Disease ID | Source | Name | Description |
| 235800 | OMIM | Histidinemia (HISTID) | Autosomal recessive disease characterized by increased histidine and histamine as well as decreased urocanic acid in body fluids. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
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| Drug | Name | Source | Type |
| DB00117 | Histidine | Drugbank | small molecule |
Interactions
0 interactions
| Interactor | Partner | Sources | Publications | Link |