Entity Details

Primary name PLGF_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49763
EntryNamePLGF_HUMAN
FullNamePlacenta growth factor
TaxID9606
Evidenceevidence at protein level
Length221
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesPGF

GO terms

Show/Hide Table
GOName
GO:0001666 response to hypoxia
GO:0001934 positive regulation of protein phosphorylation
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002040 sprouting angiogenesis
GO:0005172 vascular endothelial growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0008083 growth factor activity
GO:0008201 heparin binding
GO:0008284 positive regulation of cell population proliferation
GO:0016020 membrane
GO:0030154 cell differentiation
GO:0038084 vascular endothelial growth factor signaling pathway
GO:0042056 chemoattractant activity
GO:0045766 positive regulation of angiogenesis
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0050930 induction of positive chemotaxis
GO:0051781 positive regulation of cell division
GO:0060754 positive regulation of mast cell chemotaxis

Subcellular Location

Show/Hide Table
Subcellular Location
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR000072 PDGF/VEGF domainDomainDomain
IPR023581 Platelet-derived growth factor, conserved siteSiteConserved site
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB08885 AfliberceptDrugbankbiotech

Interactions

5 interactions