Entity Details

Primary name VEGFC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49767
EntryNameVEGFC_HUMAN
FullNameVascular endothelial growth factor C
TaxID9606
Evidenceevidence at protein level
Length419
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesVEGFC

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0001934 positive regulation of protein phosphorylation
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002040 sprouting angiogenesis
GO:0002052 positive regulation of neuroblast proliferation
GO:0002576 platelet degranulation
GO:0005172 vascular endothelial growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006929 substrate-dependent cell migration
GO:0007165 signal transduction
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0009887 animal organ morphogenesis
GO:0016020 membrane
GO:0016331 morphogenesis of embryonic epithelium
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031093 platelet alpha granule lumen
GO:0031954 positive regulation of protein autophosphorylation
GO:0038084 vascular endothelial growth factor signaling pathway
GO:0042056 chemoattractant activity
GO:0042493 response to drug
GO:0043185 vascular endothelial growth factor receptor 3 binding
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0045668 negative regulation of osteoblast differentiation
GO:0045766 positive regulation of angiogenesis
GO:0045776 negative regulation of blood pressure
GO:0045860 positive regulation of protein kinase activity
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0050714 positive regulation of protein secretion
GO:0050930 induction of positive chemotaxis
GO:0051781 positive regulation of cell division
GO:0060754 positive regulation of mast cell chemotaxis
GO:1901492 positive regulation of lymphangiogenesis
GO:1902462 positive regulation of mesenchymal stem cell proliferation
GO:1990830 cellular response to leukemia inhibitory factor

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000072 PDGF/VEGF domainDomainDomain
IPR004153 CXCXC repeatRepeatRepeat
IPR023581 Platelet-derived growth factor, conserved siteSiteConserved site
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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Interactions

4 interactions