Entity Details

Primary name CCL11_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51671
EntryNameCCL11_HUMAN
FullNameEotaxin
TaxID9606
Evidenceevidence at protein level
Length97
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCCL11

GO terms

Show/Hide Table
GOName
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002544 chronic inflammatory response
GO:0002548 monocyte chemotaxis
GO:0002551 mast cell chemotaxis
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006468 protein phosphorylation
GO:0006874 cellular calcium ion homeostasis
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0007010 cytoskeleton organization
GO:0007015 actin filament organization
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007611 learning or memory
GO:0008009 chemokine activity
GO:0008360 regulation of cell shape
GO:0009314 response to radiation
GO:0009615 response to virus
GO:0019221 cytokine-mediated signaling pathway
GO:0030335 positive regulation of cell migration
GO:0030593 neutrophil chemotaxis
GO:0030838 positive regulation of actin filament polymerization
GO:0031640 killing of cells of other organism
GO:0031728 CCR3 chemokine receptor binding
GO:0035962 response to interleukin-13
GO:0043547 positive regulation of GTPase activity
GO:0045766 positive regulation of angiogenesis
GO:0046983 protein dimerization activity
GO:0048018 receptor ligand activity
GO:0048020 CCR chemokine receptor binding
GO:0048245 eosinophil chemotaxis
GO:0048247 lymphocyte chemotaxis
GO:0050768 negative regulation of neurogenesis
GO:0060444 branching involved in mammary gland duct morphogenesis
GO:0060763 mammary duct terminal end bud growth
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0070098 chemokine-mediated signaling pathway
GO:0070371 ERK1 and ERK2 cascade
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070670 response to interleukin-4
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0090647 modulation of age-related behavioral decline

Subcellular Location

Show/Hide Table
Subcellular Location
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR000827 CC chemokine, conserved siteSiteConserved site
IPR001811 Chemokine interleukin-8-like domainDomainDomain
IPR036048 Chemokine interleukin-8-like superfamilyFamilyHomologous superfamily
IPR039809 Chemokine beta/gamma/deltaFamilyFamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB05429 CAT-213Drugbankbiotech

Interactions

31 interactions

InteractorPartnerSourcesPublicationsLink
CCL11_HUMANTPIS_HUMANHPRD, IntAct16169070 details
CCL11_HUMANDPP4_HUMANHPRD, MINT11390394 18275857 21314817 details
CCL11_HUMANNUDT3_HUMANBioGRID, MINT21900206 details
CCL11_HUMANCCR3_HUMANBioGRID, DIP, HPRD, IntAct23597562 25450766 8609214 8642344 8676064 9712872 details
CCL11_HUMANCCL5_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANPLF4_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANSDF1_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCCL8_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCXL14_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCXL11_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCXL10_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCXCL9_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCXCL6_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCXCL5_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCXCL3_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCXCL2_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANGROA_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANXCL1_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCCL28_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCCL14_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCCL13_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCCL2_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCCL18_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCCL26_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCCL27_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANPF4V_HUMANbhf-ucl, BioGRID28381538 details
CCL11_HUMANCCL11_HUMANBioGRID9712872 details
CCL11_HUMANCCR2_HUMANHPRD11264152 details
CCL11_HUMANCCR5_HUMANHPRD10477718 11264152 details
CCL11_HUMANACKR4_HUMANHPRD10734104 details
CCL11_HUMANACKR2_HUMANHPRD9405404 details