Entity Details

Primary name CAZA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP52907
EntryNameCAZA1_HUMAN
FullNameF-actin-capping protein subunit alpha-1
TaxID9606
Evidenceevidence at protein level
Length286
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCAPZA1

GO terms

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GOName
GO:0003779 actin binding
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007596 blood coagulation
GO:0008290 F-actin capping protein complex
GO:0015629 actin cytoskeleton
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030036 actin cytoskeleton organization
GO:0034329 cell junction assembly
GO:0035722 interleukin-12-mediated signaling pathway
GO:0045087 innate immune response
GO:0045296 cadherin binding
GO:0051015 actin filament binding
GO:0051016 barbed-end actin filament capping
GO:0065003 protein-containing complex assembly
GO:0070062 extracellular exosome
GO:0071203 WASH complex

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002189 F-actin-capping protein subunit alphaFamilyFamily
IPR017865 F-actin capping protein, alpha subunit, conserved siteSiteConserved site
IPR037282 F-actin-capping protein subunit alpha/betaFamilyHomologous superfamily
IPR042276 F-actin-capping protein subunit alpha/beta, domain 2FamilyHomologous superfamily
IPR042489 F-actin capping protein, alpha subunit, domain 1FamilyHomologous superfamily

Diseases

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Interactions

36 interactions

InteractorPartnerSourcesPublicationsLink
CAZA1_HUMANS10A1_HUMANHPRD, UniProt31837246 9803314 details
CAZA1_HUMANS10A5_HUMANUniProt31837246 details
CAZA1_HUMANS100B_HUMANBioGRID, HPRD, UniProt12470955 31837246 details
CAZA1_HUMANS100P_HUMANUniProt31837246 details
CAZA1_HUMANCD2AP_HUMANBioGRID, HPRD12690097 20697350 22706086 details
CAZA1_HUMANUCHL5_HUMANBioGRID21800051 details
CAZA1_HUMANHSP7C_HUMANBioGRID20884878 details
CAZA1_HUMANIKKA_HUMANIntAct14743216 details
CAZA1_HUMANNEMO_HUMANIntAct14743216 details
CAZA1_HUMANM3K3_HUMANIntAct14743216 details
CAZA1_HUMANRIPK3_HUMANIntAct14743216 details
CAZA1_HUMANNEBU_HUMANMINT16902413 details
CAZA1_HUMANEIF1B_HUMANIntAct17353931 details
CAZA1_HUMANCRCM_HUMANIntAct17353931 details
CAZA1_HUMANCNOT8_HUMANIntAct17353931 details
CAZA1_HUMANATG5_HUMANIntAct17353931 details
CAZA1_HUMANCCNA1_HUMANIntAct17353931 details
CAZA1_HUMANHLAB_HUMANIntAct17353931 details
CAZA1_HUMAN3MG_HUMANBioGRID, IntAct17353931 23537643 details
CAZA1_HUMANTRAF6_HUMANIntAct17353931 details
CAZA1_HUMANIKKE_HUMANIntAct17353931 details
CAZA1_HUMANAAKB1_HUMANIntAct17353931 details
CAZA1_HUMANSH3K1_HUMANBioGRID, HPRD, IntAct, MINT12690097 23178720 28514442 31980649 details
CAZA1_HUMANDCTN1_HUMANBioGRID, IntAct27173435 unassigned1312 details
CAZA1_HUMANDCTN2_HUMANBioGRID, IntAct27173435 unassigned1312 details
CAZA1_HUMANCPZIP_HUMANBioGRID, IntAct15850461 28514442 details
CAZA1_HUMANBLNK_HUMANBioGRID21822214 details
CAZA1_HUMANWAC2C_HUMANBioGRID22070227 details
CAZA1_HUMANRHG17_HUMANBioGRID16678097 details
CAZA1_HUMANBAG3_HUMANBioGRID20884878 details
CAZA1_HUMANMYO6_HUMANBioGRID9852149 details
CAZA1_HUMANPHB_HUMANBioGRID19725029 details
CAZA1_HUMANSIR6_HUMANBioGRID24169447 details
CAZA1_HUMANRN169_HUMANBioGRID28325877 details
CAZA1_HUMANSOX2_HUMANBioGRID21280222 details
CAZA1_HUMANACTB_HUMANHPRD8639502 details