Entity Details
| Primary name |
SCOT1_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | P55809 |
| EntryName | SCOT1_HUMAN |
| FullName | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 520 |
| SequenceStatus | complete |
| DateCreated | 1997-11-01 |
| DateModified | 2021-06-02 |
Subcellular Location
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| Subcellular Location |
| Mitochondrion matrix |
Domains
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| Domain | Name | Category | Type |
| IPR004163 | Coenzyme A transferase binding site | Site | Binding site |
| IPR004164 | Coenzyme A transferase active site | Site | Active site |
| IPR004165 | Coenzyme A transferase family I | Family | Family |
| IPR012791 | 3-oxoacid CoA-transferase, subunit B | Domain | Domain |
| IPR012792 | 3-oxoacid CoA-transferase, subunit A | Domain | Domain |
| IPR014388 | 3-oxoacid CoA-transferase | Family | Family |
| IPR037171 | NagB/RpiA transferase-like | Family | Homologous superfamily |
Diseases
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| Disease ID | Source | Name | Description |
| 245050 | OMIM | Succinyl-CoA:3-oxoacid CoA transferase deficiency (SCOTD) | A disorder of ketone body metabolism, characterized by episodic ketoacidosis. Patients are usually asymptomatic between episodes. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
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| Drug | Name | Source | Type |
| DB00139 | Succinic acid | Drugbank | small molecule |
| DB02731 | Ethylmercurithiosalicylic acid | Drugbank | small molecule |
Interactions
3 interactions