Entity Details

Primary name UCP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55851
EntryNameUCP2_HUMAN
FullNameMitochondrial uncoupling protein 2
TaxID9606
Evidenceevidence at protein level
Length309
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesUCP2

GO terms

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GOName
GO:0000303 response to superoxide
GO:0001666 response to hypoxia
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0007565 female pregnancy
GO:0007568 aging
GO:0009409 response to cold
GO:0010942 positive regulation of cell death
GO:0016021 integral component of membrane
GO:0017077 oxidative phosphorylation uncoupler activity
GO:0032869 cellular response to insulin stimulus
GO:0034198 cellular response to amino acid starvation
GO:0043066 negative regulation of apoptotic process
GO:0051881 regulation of mitochondrial membrane potential
GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070542 response to fatty acid
GO:0071333 cellular response to glucose stimulus
GO:0097421 liver regeneration
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1902600 proton transmembrane transport
GO:1990542 mitochondrial transmembrane transport
GO:1990845 adaptive thermogenesis

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR002030 Mitochondrial carrier UCP-likeFamilyFamily
IPR018108 Mitochondrial substrate/solute carrierRepeatRepeat
IPR023395 Mitochondrial carrier domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

6 interactions