Entity Details

Primary name ZP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP60852
EntryNameZP1_HUMAN
FullNameZona pellucida sperm-binding protein 1
TaxID9606
Evidenceevidence at protein level
Length638
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesZP1

GO terms

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GOName
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0007339 binding of sperm to zona pellucida
GO:0016021 integral component of membrane
GO:0035804 structural constituent of egg coat
GO:0035805 egg coat
GO:0062023 collagen-containing extracellular matrix

Subcellular Location

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Subcellular Location
Cell membrane
Zona pellucida

Domains

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DomainNameCategoryType
IPR000519 P-type trefoil domainDomainDomain
IPR001507 Zona pellucida domainDomainDomain
IPR017957 P-type trefoil, conserved siteSiteConserved site
IPR017977 Zona pellucida domain, conserved siteSiteConserved site

Diseases

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Disease IDSourceNameDescription
615774 OMIMOocyte maturation defect 1 (OOMD1)An infertility disorder caused by defective oocyte maturation that results in abnormal eggs lacking a zona pellucida. Affected females have normal menstrual cycles and sex hormone levels, no obstruction in the fallopian tubes or abnormalities of the uterus or adnexa. The disease is caused by variants affecting the gene represented in this entry.

Interactions

0 interactions

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