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Entity Details
Primary name
IRX6_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P78412
EntryName
IRX6_HUMAN
FullName
Iroquois-class homeodomain protein IRX-6
TaxID
9606
Evidence
evidence at protein level
Length
446
SequenceStatus
complete
DateCreated
1998-07-15
DateModified
2021-06-02
Ontological Relatives
Genes
IRX6
GO terms
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GO
Name
GO:0000785
chromatin
GO:0000978
RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228
DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634
nucleus
GO:0006357
regulation of transcription by RNA polymerase II
GO:0030182
neuron differentiation
GO:0045893
positive regulation of transcription, DNA-templated
GO:0048468
cell development
Subcellular Location
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Subcellular Location
Nucleus
Domains
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Domain
Name
Category
Type
IPR001356
Homeobox domain
Domain
Domain
IPR003893
Iroquois-class homeodomain protein
Domain
Domain
IPR008422
Homeobox KN domain
Domain
Domain
IPR009057
Homeobox-like domain superfamily
Family
Homologous superfamily
IPR017970
Homeobox, conserved site
Site
Conserved site
Diseases
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Drugs
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Interactions
12 interactions
Interactor
Partner
Sources
Publications
Link
IRX6_HUMAN
CRX_HUMAN
BioGRID, IntAct
32296183
details
IRX6_HUMAN
TLE5_HUMAN
BioGRID, IntAct
32296183
details
IRX6_HUMAN
GLRX3_HUMAN
BioGRID, IntAct
32296183
details
IRX6_HUMAN
MLRV_HUMAN
IntAct
32296183
details
IRX6_HUMAN
PFD5_HUMAN
BioGRID, IntAct
32296183
details
IRX6_HUMAN
ARI5A_HUMAN
BioGRID, IntAct
32296183
details
IRX6_HUMAN
IKBD_HUMAN
BioGRID, IntAct
32296183
details
IRX6_HUMAN
TRIB3_HUMAN
BioGRID, IntAct
32296183
details
IRX6_HUMAN
HXA1_HUMAN
BioGRID, IntAct
32296183
details
IRX6_HUMAN
KR197_HUMAN
BioGRID, IntAct
32296183
details
IRX6_HUMAN
TBX19_HUMAN
BioGRID, IntAct
32296183
details
IRX6_HUMAN
MEOX2_HUMAN
BioGRID
32296183
details
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