Entity Details

Primary name HTRA3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP83110
EntryNameHTRA3_HUMAN
FullNameSerine protease HTRA3
TaxID9606
Evidenceevidence at protein level
Length453
SequenceStatuscomplete
DateCreated2001-09-26
DateModified2021-06-02

Ontological Relatives

GenesHTRA3

GO terms

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GOName
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005520 insulin-like growth factor binding
GO:0005576 extracellular region
GO:0006508 proteolysis
GO:0008236 serine-type peptidase activity
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0042802 identical protein binding

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000867 Insulin-like growth factor-binding protein, IGFBPDomainDomain
IPR001478 PDZ domainDomainDomain
IPR001940 Peptidase S1CFamilyFamily
IPR002350 Kazal domainDomainDomain
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR036058 Kazal domain superfamilyFamilyHomologous superfamily
IPR041489 PDZ domain 6DomainDomain

Diseases

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