Entity Details

Primary name CPSF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ10570
EntryNameCPSF1_HUMAN
FullNameCleavage and polyadenylation specificity factor subunit 1
TaxID9606
Evidenceevidence at protein level
Length1443
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCPSF1

GO terms

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GOName
GO:0000398 mRNA splicing, via spliceosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex
GO:0006369 termination of RNA polymerase II transcription
GO:0006378 mRNA polyadenylation
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0006406 mRNA export from nucleus
GO:0019899 enzyme binding
GO:0031124 mRNA 3'-end processing
GO:0035925 mRNA 3'-UTR AU-rich region binding
GO:0098789 pre-mRNA cleavage required for polyadenylation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR004871 Cleavage/polyadenylation specificity factor, A subunit, C-terminalDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR018846 Cleavage/polyadenylation specificity factor, A subunit, N-terminalDomainDomain

Diseases

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Interactions

53 interactions

InteractorPartnerSourcesPublicationsLink
CPSF1_HUMANPRC2A_HUMANBioGRID, HPRD, IntAct14667819 details
CPSF1_HUMANWWOX_HUMANBioGRID, MINT16055720 24550385 details
CPSF1_HUMANGLIS2_HUMANBioGRID, MINT17289029 details
CPSF1_HUMANPAPOA_HUMANBioGRID, MINT21102410 7590244 details
CPSF1_HUMANREL_HUMANBioGRID, IntAct25416956 details
CPSF1_HUMANFIP1_HUMANBioGRID, DIP, IntAct14749727 22939629 24981860 26344197 26496610 29358758 29395067 29540792 details
CPSF1_HUMANDDT4L_HUMANIntAct32296183 details
CPSF1_HUMANINCA1_HUMANBioGRID, IntAct32296183 details
CPSF1_HUMANTAF7_HUMANBioGRID, HPRD9311784 details
CPSF1_HUMANTAF12_HUMANBioGRID, HPRD9311784 details
CPSF1_HUMANTAF5_HUMANBioGRID, HPRD9311784 details
CPSF1_HUMANCSTF3_HUMANBioGRID29395067 7590244 details
CPSF1_HUMANRPB1_HUMANBioGRID, HPRD9002523 9311784 details
CPSF1_HUMANNEDD4_HUMANBioGRID16055720 details
CPSF1_HUMANMYC_HUMANBioGRID, IntAct17353931 29467282 details
CPSF1_HUMANNPM_HUMANBioGRID, MINT21822216 details
CPSF1_HUMANSYMPK_HUMANBioGRID, IntAct24981860 26344197 26496610 29395067 details
CPSF1_HUMANWDR33_HUMANBioGRID, DIP22939629 24981860 26344197 29274231 29358758 29395067 29540792 details
CPSF1_HUMANCSTF2_HUMANBioGRID10669729 26344197 details
CPSF1_HUMANCSN5_HUMANBioGRID18173839 details
CPSF1_HUMANCSN2_HUMANBioGRID18173839 details
CPSF1_HUMANTBP_HUMANBioGRID9311784 details
CPSF1_HUMANSMRCD_HUMANBioGRID21549307 details
CPSF1_HUMANRBBP6_HUMANBioGRID25319826 29395067 details
CPSF1_HUMANCSN1_HUMANBioGRID18173839 details
CPSF1_HUMANZCH18_HUMANBioGRID29298432 29395067 details
CPSF1_HUMANANLN_HUMANBioGRID29395067 31586073 details
CPSF1_HUMANARI1B_HUMANBioGRID29395067 details
CPSF1_HUMANBEND3_HUMANBioGRID29395067 details
CPSF1_HUMANHAKAI_HUMANBioGRID29395067 details
CPSF1_HUMANCPSF7_HUMANBioGRID29395067 details
CPSF1_HUMANCUX1_HUMANBioGRID29395067 details
CPSF1_HUMANCASP_HUMANBioGRID29395067 details
CPSF1_HUMANDACH1_HUMANBioGRID29395067 details
CPSF1_HUMANGPTC8_HUMANBioGRID29395067 details
CPSF1_HUMANPCF11_HUMANBioGRID29395067 details
CPSF1_HUMANPRP4_HUMANBioGRID29395067 details
CPSF1_HUMANBRE1A_HUMANBioGRID29395067 details
CPSF1_HUMANSALL1_HUMANBioGRID29395067 details
CPSF1_HUMANWRN_HUMANBioGRID29395067 details
CPSF1_HUMANZN148_HUMANBioGRID29395067 details
CPSF1_HUMANNCOA2_HUMANBioGRID29395067 details
CPSF1_HUMANNCOR1_HUMANBioGRID29395067 details
CPSF1_HUMANNOP14_HUMANBioGRID29395067 details
CPSF1_HUMANQSER1_HUMANBioGRID29395067 details
CPSF1_HUMANTSH3_HUMANBioGRID29395067 details
CPSF1_HUMANTRA2B_HUMANBioGRID29395067 details
CPSF1_HUMANTRIPC_HUMANBioGRID29395067 details
CPSF1_HUMANZBT10_HUMANBioGRID29395067 details
CPSF1_HUMANCPSF1_HUMANHPRD11060040 details
CPSF1_HUMANTAF13_HUMANHPRD9311784 details
CPSF1_HUMANTAF11_HUMANHPRD9311784 details
CPSF1_HUMANMCM2_HUMANHPRD12392551 details