Entity Details

Primary name CD24
Entity type gene
Source Source Link

Details

PrimaryID100133941
RefseqGeneNG_041768
SymbolCD24
NameCD24 molecule
Chromosome6
Location6q21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2007-12-20
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsCD24_HUMAN

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0001775 cell activation
GO:0001959 regulation of cytokine-mediated signaling pathway
GO:0002237 response to molecule of bacterial origin
GO:0002768 immune response-regulating cell surface receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0009986 cell surface
GO:0016020 membrane
GO:0016055 Wnt signaling pathway
GO:0016477 cell migration
GO:0019901 protein kinase binding
GO:0030296 protein tyrosine kinase activator activity
GO:0030856 regulation of epithelial cell differentiation
GO:0031295 T cell costimulation
GO:0031362 anchored component of external side of plasma membrane
GO:0032597 B cell receptor transport into membrane raft
GO:0032600 chemokine receptor transport out of membrane raft
GO:0032913 negative regulation of transforming growth factor beta3 production
GO:0042104 positive regulation of activated T cell proliferation
GO:0042325 regulation of phosphorylation
GO:0042632 cholesterol homeostasis
GO:0043406 positive regulation of MAP kinase activity
GO:0043408 regulation of MAPK cascade
GO:0043627 response to estrogen
GO:0045121 membrane raft
GO:0045730 respiratory burst
GO:0072112 glomerular visceral epithelial cell differentiation
GO:0072139 glomerular parietal epithelial cell differentiation
GO:0097193 intrinsic apoptotic signaling pathway
GO:0098609 cell-cell adhesion
GO:2000768 positive regulation of nephron tubule epithelial cell differentiation

Diseases

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Disease IDSourceNameDescription
126200 OMIMMultiple sclerosis (MS)A multifactorial, inflammatory, demyelinating disease of the central nervous system. Sclerotic lesions are characterized by perivascular infiltration of monocytes and lymphocytes and appear as indurated areas in pathologic specimens (sclerosis in plaques). The pathological mechanism is regarded as an autoimmune attack of the myelin sheath, mediated by both cellular and humoral immunity. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia and bladder dysfunction. Genetic and environmental factors influence susceptibility to the disease. Disease susceptibility may be associated with variants affecting the gene represented in this entry.

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
CD24SELPBioGRID, HPRD9129046 details
CD24NPM1BioGRID25600590 details
CD24LYNBioGRID, HPRD, Molecular Connections22731636 8753773 details
CD24FGRBioGRID, HPRD8753773 details