Entity Details

Primary name IL18BP
Entity type gene
Source Source Link

Details

PrimaryID10068
RefseqGeneNG_029021
SymbolIL18BP
Nameinterleukin 18 binding protein
Chromosome11
Location11q13.4
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-05-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsI18BP_HUMAN

GO terms

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GOName
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0035655 interleukin-18-mediated signaling pathway
GO:0042007 interleukin-18 binding
GO:0042088 T-helper 1 type immune response
GO:0048019 receptor antagonist activity
GO:0070062 extracellular exosome
GO:0071345 cellular response to cytokine stimulus

Diseases

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Disease IDSourceNameDescription
618549 OMIMHepatitis, fulminant viral (FVH)An autosomal recessive form of fulminant viral hepatitis, a disease that strikes otherwise healthy individuals during primary infection with common liver-tropic viruses. FVH is characterized by severe liver destruction in the absence of a preexisting liver disorder, leading to encephalopathy within 8 weeks of the onset of the first symptoms. Disease susceptibility may be associated with variants affecting the gene represented in this entry.

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
IL18BPIL18BioGRID, HPRD11907126 details
IL18BPIL37HPRD12381835 details
IL18BPSTAT1IntAct19046253 details