Entity Details

Primary name RASGRP2
Entity type gene
Source Source Link

Details

PrimaryID10235
RefseqGeneNG_007574
SymbolRASGRP2
NameRAS guanyl releasing protein 2
Chromosome11
Location11q13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-15
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsGRP2_HUMAN

GO terms

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GOName
GO:0001558 regulation of cell growth
GO:0002250 adaptive immune response
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0007265 Ras protein signal transduction
GO:0008289 lipid binding
GO:0019992 diacylglycerol binding
GO:0032587 ruffle membrane
GO:0043005 neuron projection
GO:0043547 positive regulation of GTPase activity
GO:0045202 synapse
GO:0071277 cellular response to calcium ion

Diseases

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Disease IDSourceNameDescription
615888 OMIMBleeding disorder, platelet-type 18 (BDPLT18)A disorder characterized by increased bleeding tendency due to platelet dysfunction. Clinical features include epistaxis, hematomas, bleeding after tooth extraction, and menorrhagia. The disease is caused by variants affecting the gene represented in this entry.

Interactions

6 interactions