Entity Details

Primary name ZP4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ12836
EntryNameZP4_HUMAN
FullNameZona pellucida sperm-binding protein 4
TaxID9606
Evidenceevidence at protein level
Length540
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesZP4

GO terms

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GOName
GO:0002922 positive regulation of humoral immune response
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0007339 binding of sperm to zona pellucida
GO:0016021 integral component of membrane
GO:0032190 acrosin binding
GO:0035804 structural constituent of egg coat
GO:0035805 egg coat
GO:0042102 positive regulation of T cell proliferation
GO:0042802 identical protein binding
GO:0060478 acrosomal vesicle exocytosis
GO:2000344 positive regulation of acrosome reaction
GO:2000360 negative regulation of binding of sperm to zona pellucida

Subcellular Location

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Subcellular Location
Cell membrane
Zona pellucida

Domains

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DomainNameCategoryType
IPR000519 P-type trefoil domainDomainDomain
IPR001507 Zona pellucida domainDomainDomain
IPR017957 P-type trefoil, conserved siteSiteConserved site
IPR017977 Zona pellucida domain, conserved siteSiteConserved site

Diseases

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