Entity Details

Primary name SIK1B
Entity type gene
Source Source Link

Details

PrimaryID102724428
RefseqGene
SymbolSIK1B
Namesalt inducible kinase 1B (putative)
Chromosome21
Location21p12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2014-01-30
ModificationDate2021-06-22

Ontological Relatives

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0002028 regulation of sodium ion transport
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006468 protein phosphorylation
GO:0007049 cell cycle
GO:0007346 regulation of mitotic cell cycle
GO:0008140 cAMP response element binding protein binding
GO:0010830 regulation of myotube differentiation
GO:0010868 negative regulation of triglyceride biosynthetic process
GO:0019901 protein kinase binding
GO:0032792 negative regulation of CREB transcription factor activity
GO:0035556 intracellular signal transduction
GO:0042149 cellular response to glucose starvation
GO:0043153 entrainment of circadian clock by photoperiod
GO:0045595 regulation of cell differentiation
GO:0045721 negative regulation of gluconeogenesis
GO:0046777 protein autophosphorylation
GO:0048511 rhythmic process
GO:0055007 cardiac muscle cell differentiation
GO:0071889 14-3-3 protein binding
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000210 positive regulation of anoikis

Diseases

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Disease IDSourceNameDescription
616341 OMIMDevelopmental and epileptic encephalopathy 30 (DEE30)A form of epileptic encephalopathy, a heterogeneous group of severe childhood onset epilepsies characterized by refractory seizures, neurodevelopmental impairment, and poor prognosis. Development is normal prior to seizure onset, after which cognitive and motor delays become apparent. The disease is caused by variants affecting the gene represented in this entry.