Entity Details

Primary name CACNG2
Entity type gene
Source Source Link

Details

PrimaryID10369
RefseqGeneNG_031861
SymbolCACNG2
Namecalcium voltage-gated channel auxiliary subunit gamma 2
Chromosome22
Location22q12.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-06-11
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCCG2_HUMAN

GO terms

Show/Hide Table
GOName
GO:0005245 voltage-gated calcium channel activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005891 voltage-gated calcium channel complex
GO:0006612 protein targeting to membrane
GO:0007528 neuromuscular junction development
GO:0009986 cell surface
GO:0016247 channel regulator activity
GO:0019226 transmission of nerve impulse
GO:0030666 endocytic vesicle membrane
GO:0032281 AMPA glutamate receptor complex
GO:0035255 ionotropic glutamate receptor binding
GO:0036477 somatodendritic compartment
GO:0044300 cerebellar mossy fiber
GO:0051592 response to calcium ion
GO:0051899 membrane depolarization
GO:0051968 positive regulation of synaptic transmission, glutamatergic
GO:0060081 membrane hyperpolarization
GO:0060082 eye blink reflex
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098686 hippocampal mossy fiber to CA3 synapse
GO:0098839 postsynaptic density membrane
GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome
GO:0098970 postsynaptic neurotransmitter receptor diffusion trapping
GO:0098978 glutamatergic synapse
GO:0099061 integral component of postsynaptic density membrane
GO:0099590 neurotransmitter receptor internalization
GO:1904510 positive regulation of protein localization to basolateral plasma membrane
GO:2000311 regulation of AMPA receptor activity
GO:2000969 positive regulation of AMPA receptor activity

Diseases

Show/Hide Table
Disease IDSourceNameDescription
614256 OMIMMental retardation, autosomal dominant 10 (MRD10)A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. The disease is caused by variants affecting the gene represented in this entry.