Entity Details

Primary name TREH
Entity type gene
Source Source Link

Details

PrimaryID11181
RefseqGeneNG_023321
SymbolTREH
Nametrehalase
Chromosome11
Location11q23.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-08
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTREA_HUMAN

GO terms

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GOName
GO:0004555 alpha,alpha-trehalase activity
GO:0005991 trehalose metabolic process
GO:0005993 trehalose catabolic process
GO:0009887 animal organ morphogenesis
GO:0031225 anchored component of membrane
GO:0046658 anchored component of plasma membrane
GO:0070062 extracellular exosome

Diseases

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Disease IDSourceNameDescription
612119 OMIMTrehalase deficiency (TREHD)An autosomal recessive condition characterized by the inability to digest trehalose, a disaccharide found in mushrooms, products containing baker's yeast, and dried food. Individuals with trehalase deficiency suffer from abdominal pain, increased rectal flatulence, and diarrhea due to osmotic water flow into the colon. The gene represented in this entry is involved in disease pathogenesis.

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TREHGPAA1BioGRID, IntAct28514442 details