Entity Details

Primary name CHRNA2
Entity type gene
Source Source Link

Details

PrimaryID1135
RefseqGeneNG_015827
SymbolCHRNA2
Namecholinergic receptor nicotinic alpha 2 subunit
Chromosome8
Location8p21.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-10-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsACHA2_HUMAN

GO terms

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GOName
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005892 acetylcholine-gated channel complex
GO:0006811 ion transport
GO:0007165 signal transduction
GO:0007268 chemical synaptic transmission
GO:0007271 synaptic transmission, cholinergic
GO:0015464 acetylcholine receptor activity
GO:0016021 integral component of membrane
GO:0022848 acetylcholine-gated cation-selective channel activity
GO:0030594 neurotransmitter receptor activity
GO:0034220 ion transmembrane transport
GO:0035094 response to nicotine
GO:0042391 regulation of membrane potential
GO:0043005 neuron projection
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0050877 nervous system process

Diseases

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Disease IDSourceNameDescription
610353 OMIMEpilepsy, nocturnal frontal lobe, 4 (ENFL4)An autosomal dominant focal epilepsy characterized by nocturnal seizures associated with fear sensation, tongue movements, and nocturnal wandering, closely resembling nightmares and sleep walking. The disease is caused by variants affecting the gene represented in this entry.
610353 OMIMEpilepsy, nocturnal frontal lobe, 4 (ENFL4)An autosomal dominant focal epilepsy characterized by nocturnal seizures associated with fear sensation, tongue movements, and nocturnal wandering, closely resembling nightmares and sleep walking. The disease may be caused by variants affecting the gene represented in this entry.

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CHRNA2CHRNB2HPRD8906617 details
CHRNA2CHRNB4HPRD8906617 details