Entity Details

Primary name CNTF
Entity type gene
Source Source Link

Details

PrimaryID1270
RefseqGeneNG_008776
SymbolCNTF
Nameciliary neurotrophic factor
Chromosome11
Location11q12.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1991-10-30
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCNTF_HUMAN

GO terms

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GOName
GO:0005125 cytokine activity
GO:0005127 ciliary neurotrophic factor receptor binding
GO:0005138 interleukin-6 receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007165 signal transduction
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0019221 cytokine-mediated signaling pathway
GO:0030424 axon
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0043524 negative regulation of neuron apoptotic process
GO:0044877 protein-containing complex binding
GO:0046533 negative regulation of photoreceptor cell differentiation
GO:0046668 regulation of retinal cell programmed cell death
GO:0048143 astrocyte activation
GO:0048644 muscle organ morphogenesis
GO:0048666 neuron development
GO:0048680 positive regulation of axon regeneration
GO:0070120 ciliary neurotrophic factor-mediated signaling pathway

Diseases

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Interactions

27 interactions

InteractorPartnerSourcesPublicationsLink
CNTFLIFRHPRD, IntAct, MINT12643274 16051226 18775332 details
CNTFIL6STHPRD, IntAct, MINT12643274 16051226 18775332 details
CNTFTRIP6BioGRID, IntAct25416956 details
CNTFKRT40BioGRID, IntAct25416956 details
CNTFCNTFRBioGRID, HPRD, IntAct10812968 18775332 20584990 7810882 8627290 details
CNTFKRT31BioGRID, IntAct32296183 details
CNTFNDUFAB1BioGRID, IntAct32296183 details
CNTFTEPSINBioGRID, IntAct32296183 details
CNTFCYSRT1BioGRID, IntAct32296183 details
CNTFAK8BioGRID, IntAct32296183 details
CNTFRDM1BioGRID, IntAct32296183 details
CNTFSORT1IntAct20584990 details
CNTFAPOEHPRD, IntAct32814053 9236223 details
CNTFAPPIntAct32814053 details
CNTFIL6RBioGRID, HPRD12643274 1281789 details
CNTFCNTFBioGRID, HPRD7796798 details
CNTFEXT2BioGRID, IntAct17353931 details
CNTFVHLBioGRID, IntAct17353931 details
CNTFSTK16BioGRID, IntAct17353931 details
CNTFICA1BioGRID, IntAct17353931 details
CNTFEXT1BioGRID, IntAct17353931 details
CNTFEIF3EBioGRID, IntAct17353931 details
CNTFFEM1BBioGRID, IntAct28514442 details
CNTFRBM12BioGRID, IntAct28514442 details
CNTFCORO7BioGRID, IntAct28514442 details
CNTFCHMBioGRID, IntAct28514442 details
CNTFEGFRBioGRID28065597 details