Entity Details

Primary name SLAF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13291
EntryNameSLAF1_HUMAN
FullNameSignaling lymphocytic activation molecule
TaxID9606
Evidenceevidence at protein level
Length335
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesSLAMF1

GO terms

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GOName
GO:0001618 virus receptor activity
GO:0002250 adaptive immune response
GO:0002277 myeloid dendritic cell activation involved in immune response
GO:0003823 antigen binding
GO:0004888 transmembrane signaling receptor activity
GO:0005886 plasma membrane
GO:0006909 phagocytosis
GO:0007155 cell adhesion
GO:0008284 positive regulation of cell population proliferation
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0032695 negative regulation of interleukin-12 production
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0042169 SH2 domain binding
GO:0042802 identical protein binding
GO:0045087 innate immune response
GO:0046330 positive regulation of JNK cascade
GO:0046649 lymphocyte activation
GO:0070062 extracellular exosome
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:2000349 negative regulation of CD40 signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR007110 Immunoglobulin-like domainDomainDomain
IPR010407 Signaling lymphocytic activation molecule, N-terminalDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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