Entity Details

Primary name TUSC3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13454
EntryNameTUSC3_HUMAN
FullNameTumor suppressor candidate 3
TaxID9606
Evidenceevidence at protein level
Length348
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesTUSC3

GO terms

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GOName
GO:0005739 mitochondrion
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006487 protein N-linked glycosylation
GO:0008250 oligosaccharyltransferase complex
GO:0015095 magnesium ion transmembrane transporter activity
GO:0015693 magnesium ion transport
GO:0018279 protein N-linked glycosylation via asparagine
GO:0019082 viral protein processing
GO:0050890 cognition
GO:0055085 transmembrane transport

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR021149 Oligosaccharyl transferase complex, subunit OST3/OST6FamilyFamily
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
611093 OMIMMental retardation, autosomal recessive 7 (MRT7)A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. The disease is caused by variants affecting the gene represented in this entry.

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TUSC3_HUMANPP1A_HUMANBioGRID, HPRD, MINT15231748 details
TUSC3_HUMANBMI1_HUMANBioGRID19451220 details