Entity Details

Primary name APCDD1
Entity type gene
Source Source Link

Details

PrimaryID147495
RefseqGeneNG_027685
SymbolAPCDD1
NameAPC down-regulated 1
Chromosome18
Location18p11.22
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-01-22
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAPCD1_HUMAN

GO terms

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GOName
GO:0001942 hair follicle development
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016055 Wnt signaling pathway
GO:0017147 Wnt-protein binding
GO:0030178 negative regulation of Wnt signaling pathway
GO:0042802 identical protein binding

Diseases

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Disease IDSourceNameDescription
605389 OMIMHypotrichosis 1 (HYPT1)A rare form of non-syndromic hereditary hypotrichosis without characteristic hair shaft anomalies. Affected individuals typically show normal hair at birth, but hair loss and thinning of the hair shaft start during early childhood and progress with age. HYPT1 inheritance is autosomal dominant. The disease is caused by variants affecting the gene represented in this entry.

Interactions

8 interactions