Entity Details

Primary name CLDN19
Entity type gene
Source Source Link

Details

PrimaryID149461
RefseqGeneNG_008993
SymbolCLDN19
Nameclaudin 19
Chromosome1
Location1p34.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-01-22
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCLD19_HUMAN

GO terms

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GOName
GO:0001934 positive regulation of protein phosphorylation
GO:0005198 structural molecule activity
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0005923 bicellular tight junction
GO:0007155 cell adhesion
GO:0007601 visual perception
GO:0008285 negative regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
GO:0019227 neuronal action potential propagation
GO:0030336 negative regulation of cell migration
GO:0031532 actin cytoskeleton reorganization
GO:0042802 identical protein binding
GO:0043296 apical junction complex
GO:0048471 perinuclear region of cytoplasm
GO:0050896 response to stimulus
GO:0061045 negative regulation of wound healing
GO:0070830 bicellular tight junction assembly
GO:0150111 regulation of transepithelial transport
GO:1901890 positive regulation of cell junction assembly

Diseases

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Disease IDSourceNameDescription
248190 OMIMHypomagnesemia 5, renal, with or without ocular involvement (HOMG5)A progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. The renal phenotype is virtually undistinguishable from that of patients with HOMG3. The disease is caused by variants affecting the gene represented in this entry.

Interactions

66 interactions

InteractorPartnerSourcesPublicationsLink
CLDN19CLDN16DIP, MINT19706394 22373575 details
CLDN19SRPK2BioGRID, IntAct23602568 details
CLDN19GGT7BioGRID, IntAct32296183 details
CLDN19KRT31BioGRID, IntAct32296183 details
CLDN19STOMBioGRID, IntAct32296183 details
CLDN19MS4A4ABioGRID, IntAct32296183 details
CLDN19TMEM106CBioGRID, IntAct32296183 details
CLDN19CD74BioGRID, IntAct32296183 details
CLDN19PLEKHB2BioGRID, IntAct32296183 details
CLDN19TNFSF14BioGRID, IntAct32296183 details
CLDN19KELBioGRID, IntAct32296183 details
CLDN19HSD17B13BioGRID, IntAct32296183 details
CLDN19TM4SF18BioGRID, IntAct32296183 details
CLDN19CLEC14ABioGRID, IntAct32296183 details
CLDN19LRRC25BioGRID, IntAct32296183 details
CLDN19TMEM248BioGRID, IntAct32296183 details
CLDN19IL3RABioGRID, IntAct32296183 details
CLDN19AQP9BioGRID, IntAct32296183 details
CLDN19MUC1BioGRID, IntAct32296183 details
CLDN19SUSD3BioGRID, IntAct32296183 details
CLDN19CD200R1BioGRID, IntAct32296183 details
CLDN19FCGRTBioGRID, IntAct32296183 details
CLDN19BTN2A1BioGRID, IntAct32296183 details
CLDN19SAR1ABioGRID, IntAct32296183 details
CLDN19GPR161BioGRID, IntAct32296183 details
CLDN19SGPL1BioGRID, IntAct32296183 details
CLDN19PDZK1IP1BioGRID, IntAct32296183 details
CLDN19SCARB2BioGRID, IntAct32296183 details
CLDN19SLAMF6BioGRID, IntAct32296183 details
CLDN19TMEM52BBioGRID, IntAct32296183 details
CLDN19FKBP7BioGRID, IntAct32296183 details
CLDN19AQP6BioGRID, IntAct32296183 details
CLDN19FNDC9BioGRID, IntAct32296183 details
CLDN19LRRC4CBioGRID, IntAct32296183 details
CLDN19GORABBioGRID, IntAct32296183 details
CLDN19CLRN1BioGRID, IntAct32296183 details
CLDN19FCGR1ABioGRID, IntAct32296183 details
CLDN19CD53BioGRID, IntAct32296183 details
CLDN19SPACA1BioGRID, IntAct32296183 details
CLDN19ICAM3BioGRID, IntAct32296183 details
CLDN19FAM209ABioGRID, IntAct32296183 details
CLDN19LAPTM5BioGRID, IntAct32296183 details
CLDN19SYNE4BioGRID, IntAct32296183 details
CLDN19MFFBioGRID, IntAct32296183 details
CLDN19LOC100653049IntAct32296183 details
CLDN19KRT34BioGRID, IntAct32296183 details
CLDN19CYSRT1BioGRID, IntAct32296183 details
CLDN19STOML3BioGRID, IntAct32296183 details
CLDN19CXCR3BioGRID, IntAct32296183 details
CLDN19MS4A14BioGRID, IntAct32296183 details
CLDN19CLEC2DBioGRID, IntAct32296183 details
CLDN19BIKBioGRID, IntAct32296183 details
CLDN19BCL2L13BioGRID, IntAct32296183 details
CLDN19GJA8BioGRID, IntAct32296183 details
CLDN19GPX8BioGRID, IntAct32296183 details
CLDN19TMEM80BioGRID, IntAct32296183 details
CLDN19KIR2DL3BioGRID, IntAct32296183 details
CLDN19SLC35C2BioGRID, IntAct32296183 details
CLDN19ERGIC3BioGRID, IntAct32296183 details
CLDN19IFNGR2BioGRID, IntAct32296183 details
CLDN19SLC10A1BioGRID, IntAct32296183 details
CLDN19PVRBioGRID, IntAct32296183 details
CLDN19CREB3BioGRID, IntAct25910212 details
CLDN19PKD2L1BioGRID, IntAct25910212 details
CLDN19CLDN18DIP19706394 details
CLDN19BSCL2BioGRID32296183 details