Entity Details

Primary name ASAH1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13510
EntryNameASAH1_HUMAN
FullNameAcid ceramidase
TaxID9606
Evidenceevidence at protein level
Length395
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesASAH1

GO terms

Show/Hide Table
GOName
GO:0003714 transcription corepressor activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005764 lysosome
GO:0006631 fatty acid metabolic process
GO:0006687 glycosphingolipid metabolic process
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0016922 nuclear receptor binding
GO:0017040 N-acylsphingosine amidohydrolase activity
GO:0017064 fatty acid amide hydrolase activity
GO:0030216 keratinocyte differentiation
GO:0043202 lysosomal lumen
GO:0043312 neutrophil degranulation
GO:0046512 sphingosine biosynthetic process
GO:0046513 ceramide biosynthetic process
GO:0046514 ceramide catabolic process
GO:0050810 regulation of steroid biosynthetic process
GO:0062098 regulation of programmed necrotic cell death
GO:0070062 extracellular exosome
GO:0071356 cellular response to tumor necrosis factor
GO:0102121 ceramidase activity
GO:1903507 negative regulation of nucleic acid-templated transcription
GO:1904724 tertiary granule lumen
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Lysosome
Nucleus
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR016699 Acid ceramidase-likeFamilyFamily
IPR029130 Acid ceramidase, N-terminalDomainDomain
IPR029132 Choloylglycine hydrolase/NAAA C-terminalDomainDomain

Diseases

Show/Hide Table

Interactions

7 interactions