Entity Details

Primary name AT1A4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13733
EntryNameAT1A4_HUMAN
FullNameSodium/potassium-transporting ATPase subunit alpha-4
TaxID9606
Evidenceevidence at protein level
Length1029
SequenceStatuscomplete
DateCreated2001-10-18
DateModified2021-06-02

Ontological Relatives

GenesATP1A4

GO terms

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GOName
GO:0005391 P-type sodium:potassium-exchanging transporter activity
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005890 sodium:potassium-exchanging ATPase complex
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0006814 sodium ion transport
GO:0006883 cellular sodium ion homeostasis
GO:0007166 cell surface receptor signaling pathway
GO:0007283 spermatogenesis
GO:0009566 fertilization
GO:0019829 ATPase-coupled cation transmembrane transporter activity
GO:0019900 kinase binding
GO:0030007 cellular potassium ion homeostasis
GO:0030317 flagellated sperm motility
GO:0030641 regulation of cellular pH
GO:0034220 ion transmembrane transport
GO:0035725 sodium ion transmembrane transport
GO:0036376 sodium ion export across plasma membrane
GO:0042391 regulation of membrane potential
GO:0045121 membrane raft
GO:0046872 metal ion binding
GO:0071805 potassium ion transmembrane transport
GO:0097225 sperm midpiece
GO:0097733 photoreceptor cell cilium
GO:0120200 rod photoreceptor outer segment
GO:0150104 transport across blood-brain barrier
GO:1902600 proton transmembrane transport
GO:1903779 regulation of cardiac conduction
GO:1990573 potassium ion import across plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001757 P-type ATPaseFamilyFamily
IPR004014 Cation-transporting P-type ATPase, N-terminalDomainDomain
IPR005775 P-type ATPase subfamily IIC, subunit alphaFamilyFamily
IPR006068 Cation-transporting P-type ATPase, C-terminalDomainDomain
IPR008250 P-type ATPase, A domain superfamilyFamilyHomologous superfamily
IPR018303 P-type ATPase, phosphorylation sitePTMPTM
IPR023214 HAD superfamilyFamilyHomologous superfamily
IPR023298 P-type ATPase, transmembrane domain superfamilyFamilyHomologous superfamily
IPR023299 P-type ATPase, cytoplasmic domain NFamilyHomologous superfamily
IPR036412 HAD-like superfamilyFamilyHomologous superfamily
IPR044492 P-type ATPase, haloacid dehalogenase domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB09479 Rubidium Rb-82Swissprotsmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
AT1A4_HUMANCTG1B_HUMANBioGRID, IntAct32296183 details
AT1A4_HUMANRIC8A_HUMANBioGRID, IntAct32296183 details
AT1A4_HUMANTP4A3_HUMANIntAct17353931 details