Entity Details

Primary name EGR1
Entity type gene
Source Source Link

Details

PrimaryID1958
RefseqGeneNG_021374
SymbolEGR1
Nameearly growth response 1
Chromosome5
Location5q31.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-10
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsEGR1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001666 response to hypoxia
GO:0002931 response to ischemia
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008270 zinc ion binding
GO:0009749 response to glucose
GO:0010385 double-stranded methylated DNA binding
GO:0010628 positive regulation of gene expression
GO:0030217 T cell differentiation
GO:0030509 BMP signaling pathway
GO:0032722 positive regulation of chemokine production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032868 response to insulin
GO:0032922 circadian regulation of gene expression
GO:0033233 regulation of protein sumoylation
GO:0035035 histone acetyltransferase binding
GO:0035914 skeletal muscle cell differentiation
GO:0042981 regulation of apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0044729 hemi-methylated DNA-binding
GO:0044849 estrous cycle
GO:0045475 locomotor rhythm
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046886 positive regulation of hormone biosynthetic process
GO:0060086 circadian temperature homeostasis
GO:0060337 type I interferon signaling pathway
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070498 interleukin-1-mediated signaling pathway
GO:0071480 cellular response to gamma radiation
GO:0071504 cellular response to heparin
GO:0071506 cellular response to mycophenolic acid
GO:0072110 glomerular mesangial cell proliferation
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0098759 cellular response to interleukin-8
GO:1901216 positive regulation of neuron death
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1902949 positive regulation of tau-protein kinase activity
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990841 promoter-specific chromatin binding
GO:2000182 regulation of progesterone biosynthetic process

Diseases

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Interactions

56 interactions

InteractorPartnerSourcesPublicationsLink
EGR1TP53BioGRID, HPRD, MINT11251186 14744935 15225550 21325822 details
EGR1CDKN2ABioGRID, HPRD, MINT19057511 details
EGR1EP300BioGRID, HPRD, MINT15225550 20018936 20089040 9806899 details
EGR1SREBF2BioGRID, IntAct20936779 details
EGR1NAB1BioGRID, HPRD, IntAct28514442 7624335 details
EGR1CREBBPBioGRID, HPRD9806899 details
EGR1CEBPBBioGRID, HPRD12947119 22260630 details
EGR1NAB2BioGRID, HPRD8668170 details
EGR1PITX1BioGRID, HPRD10082522 details
EGR1NFATC1BioGRID12560487 details
EGR1PSMA3BioGRID, HPRD12379479 details
EGR1RELABioGRID, HPRD10671503 details
EGR1ERBB3BioGRID12840049 details
EGR1IL1BBioGRID22455954 details
EGR1SRA1BioGRID20398657 details
EGR1WT1BioGRID19067769 details
EGR1DNMT3LBioGRID24952347 details
EGR1CRBNBioGRID30385546 details
EGR1NGFRBioGRID18378044 details
EGR1SUMO1MINT19057511 details
EGR1SNAI1BioGRID, MINT20121949 details
EGR1SP1BioGRID, HPRD, MINT12569082 20121949 details
EGR1CTNNB1BioGRID, I2D21743491 details
EGR1PFDN5BioGRID18281035 details
EGR1TBX2BioGRID20348948 details
EGR1PTENBioGRID21354147 details
EGR1MDM2BioGRID15225550 details
EGR1NFATC2BioGRID, HPRD12560487 27637333 details
EGR1CIDECBioGRID24742676 details
EGR1NTRK1BioGRID18378044 details
EGR1CSNK2A1HPRD8662759 details
EGR1JUNHPRD11278640 details
EGR1VDRMINT20089040 details
EGR1LEF1I2D21743491 details
EGR1TCF4I2D21743491 details
EGR1ARID2BioGRID, IntAct26496610 details
EGR1DNAJC8BioGRID, IntAct26496610 details
EGR1MED6BioGRID, IntAct26496610 details
EGR1MAGEB2BioGRID, IntAct26496610 details
EGR1FOSL2BioGRID, IntAct26496610 details
EGR1PHIPBioGRID, IntAct26496610 details
EGR1PSMD2BioGRID, IntAct26496610 details
EGR1JUNBBioGRID, IntAct26496610 details
EGR1POP1BioGRID, IntAct26496610 details
EGR1JUNDBioGRID, IntAct26496610 details
EGR1MIDNBioGRID, IntAct28514442 details
EGR1WDFY1BioGRID, IntAct28514442 details
EGR1NESBioGRID, IntAct28514442 details
EGR1TP53BP1BioGRID29656893 details
EGR1BRCA1BioGRID29656893 details
EGR1ATF2IntAct22439931 details
EGR1TLE1IntAct22439931 details
EGR1HDAC1IntAct22439931 details
EGR1EZH2IntAct22439931 details
EGR1CCL21IntAct33179750 details
EGR1MTDHBioGRID22199357 details