Entity Details

Primary name FGF1
Entity type gene
Source Source Link

Details

PrimaryID2246
RefseqGene
SymbolFGF1
Namefibroblast growth factor 1
Chromosome5
Location5q31.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-02-20
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsFGF1_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000187 obsolete activation of MAPK activity
GO:0001525 angiogenesis
GO:0001759 organ induction
GO:0001934 positive regulation of protein phosphorylation
GO:0005104 fibroblast growth factor receptor binding
GO:0005178 integrin binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005938 cell cortex
GO:0007165 signal transduction
GO:0007275 multicellular organism development
GO:0008083 growth factor activity
GO:0008201 heparin binding
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009653 anatomical structure morphogenesis
GO:0009887 animal organ morphogenesis
GO:0010595 positive regulation of endothelial cell migration
GO:0010628 positive regulation of gene expression
GO:0030154 cell differentiation
GO:0030324 lung development
GO:0030334 regulation of cell migration
GO:0030335 positive regulation of cell migration
GO:0030544 Hsp70 protein binding
GO:0031012 extracellular matrix
GO:0032148 activation of protein kinase B activity
GO:0034605 cellular response to heat
GO:0042060 wound healing
GO:0043406 positive regulation of MAP kinase activity
GO:0044548 S100 protein binding
GO:0045542 positive regulation of cholesterol biosynthetic process
GO:0045766 positive regulation of angiogenesis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051781 positive regulation of cell division
GO:0051897 positive regulation of protein kinase B signaling
GO:0060681 branch elongation involved in ureteric bud branching
GO:0072163 mesonephric epithelium development
GO:1901509 regulation of endothelial tube morphogenesis
GO:1902533 positive regulation of intracellular signal transduction
GO:1903672 positive regulation of sprouting angiogenesis
GO:2000347 positive regulation of hepatocyte proliferation
GO:2000544 regulation of endothelial cell chemotaxis to fibroblast growth factor

Diseases

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Interactions

32 interactions

InteractorPartnerSourcesPublicationsLink
FGF1FGFR2BioGRID, DIP, IntAct, MINT10618369 11069186 11714710 1697263 18199118 22955284 25241761 7499435 8576175 9700203 details
FGF1FGFR3BioGRID, DIP, HPRD, IntAct10574949 14613973 14732692 22244757 22955284 8576175 details
FGF1FGFR1BioGRID, DIP, HPRD, IntAct, matrixdb, UniProt10336501 10748122 10830168 11030354 11032250 11714710 1309595 1383494 14613973 1697263 1709094 18199118 18261743 18441324 22244757 22955284 25241761 28769084 8321198 8576175 8692946 8756477 9624181 details
FGF1FGF1BioGRID, HPRD, UniProt11069186 11432880 9655399 details
FGF1SRPK1IntAct23602568 details
FGF1FGFR4BioGRID, HPRD, IntAct10336501 10736564 11714710 1709094 25241761 details
FGF1VBP1BioGRID, IntAct32296183 details
FGF1CSNK2BBioGRID, HPRD12145206 details
FGF1CSNK2A1BioGRID, HPRD12145206 details
FGF1CSNK2A2BioGRID, HPRD12145206 details
FGF1S100A13BioGRID, HPRD11432880 9712836 details
FGF1HSPA9BioGRID, HPRD10510314 details
FGF1FIBPBioGRID, HPRD9806903 details
FGF1SYT1BioGRID, HPRD11432880 details
FGF1FGFBP1BioGRID, HPRD11509569 details
FGF1PTX3BioGRID25912421 details
FGF1RPS2HPRD16263090 details
FGF1NRP1HPRD15695515 details
FGF1HSPG2matrixdb24509440 details
FGF1CLDN10BioGRID, IntAct26186194 28514442 details
FGF1GPC1BioGRID, IntAct26186194 28514442 details
FGF1HMG20ABioGRID, IntAct26186194 28514442 details
FGF1EGFLAMBioGRID, IntAct26186194 28514442 details
FGF1GSE1BioGRID, IntAct26186194 28514442 details
FGF1TGFBR3BioGRID, IntAct26186194 28514442 details
FGF1GPC3BioGRID, IntAct28514442 details
FGF1SDC2BioGRID, IntAct26186194 28514442 details
FGF1SDC4BioGRID, IntAct26186194 28514442 details
FGF1RCOR1BioGRID26186194 details
FGF1RCOR3BioGRID26186194 details
FGF1KDM1ABioGRID26186194 details
FGF1GPC6BioGRID26186194 details