Entity Details

Primary name NUCG_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14249
EntryNameNUCG_HUMAN
FullNameEndonuclease G, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length297
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesENDOG

GO terms

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GOName
GO:0000014 single-stranded DNA endodeoxyribonuclease activity
GO:0001701 in utero embryonic development
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity
GO:0004521 endoribonuclease activity
GO:0005634 nucleus
GO:0005743 mitochondrial inner membrane
GO:0005829 cytosol
GO:0006309 apoptotic DNA fragmentation
GO:0006310 DNA recombination
GO:0007568 aging
GO:0009612 response to mechanical stimulus
GO:0032355 response to estradiol
GO:0034612 response to tumor necrosis factor
GO:0036475 neuron death in response to oxidative stress
GO:0043065 positive regulation of apoptotic process
GO:0043204 perikaryon
GO:0046677 response to antibiotic
GO:0046872 metal ion binding
GO:0071277 cellular response to calcium ion
GO:0071333 cellular response to glucose stimulus
GO:0071456 cellular response to hypoxia
GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death
GO:1902512 positive regulation of apoptotic DNA fragmentation

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR001604 DNA/RNA non-specific endonucleaseDomainDomain
IPR018524 DNA/RNA non-specific endonuclease, active siteSiteActive site
IPR020821 Extracellular Endonuclease, subunit ADomainDomain
IPR040255 Non-specific endonucleaseFamilyFamily

Diseases

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