Entity Details
| Primary name |
FGL2_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q14314 |
| EntryName | FGL2_HUMAN |
| FullName | Fibroleukin |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 439 |
| SequenceStatus | complete |
| DateCreated | 2001-01-11 |
| DateModified | 2021-06-02 |
GO terms
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| GO | Name |
| GO:0002291 | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell |
| GO:0002605 | negative regulation of dendritic cell antigen processing and presentation |
| GO:0002617 | negative regulation of macrophage antigen processing and presentation |
| GO:0005102 | signaling receptor binding |
| GO:0005576 | extracellular region |
| GO:0005577 | fibrinogen complex |
| GO:0005615 | extracellular space |
| GO:0008233 | peptidase activity |
| GO:0043312 | neutrophil degranulation |
| GO:0043381 | negative regulation of memory T cell differentiation |
| GO:0050687 | negative regulation of defense response to virus |
| GO:0062023 | collagen-containing extracellular matrix |
| GO:0070062 | extracellular exosome |
| GO:1904813 | ficolin-1-rich granule lumen |
Subcellular Location
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| Subcellular Location |
| Secreted |
Domains
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| Domain | Name | Category | Type |
| IPR002181 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain | Domain | Domain |
| IPR020837 | Fibrinogen, conserved site | Site | Conserved site |
| IPR033083 | Fibroleukin | Family | Family |
| IPR036056 | Fibrinogen-like, C-terminal | Family | Homologous superfamily |
Interactions
1 interaction