Entity Details

Primary name FSHB
Entity type gene
Source Source Link

Details

PrimaryID2488
RefseqGeneNG_008144
SymbolFSHB
Namefollicle stimulating hormone subunit beta
Chromosome11
Location11p14.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1989-05-24
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsFSHB_HUMAN

GO terms

Show/Hide Table
GOName
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0006701 progesterone biosynthetic process
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007292 female gamete generation
GO:0007565 female pregnancy
GO:0008284 positive regulation of cell population proliferation
GO:0009755 hormone-mediated signaling pathway
GO:0010469 regulation of signaling receptor activity
GO:0010628 positive regulation of gene expression
GO:0010893 positive regulation of steroid biosynthetic process
GO:0016486 peptide hormone processing
GO:0016913 follicle-stimulating hormone activity
GO:0016914 follicle-stimulating hormone complex
GO:0030335 positive regulation of cell migration
GO:0042699 follicle-stimulating hormone signaling pathway
GO:0045670 regulation of osteoclast differentiation
GO:0045780 positive regulation of bone resorption
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060011 Sertoli cell proliferation

Diseases

Show/Hide Table
Disease IDSourceNameDescription
229070 OMIMHypogonadotropic hypogonadism 24 without anosmia (HH24)A form of hypogonadotropic hypogonadism, a group of disorders characterized by absent or incomplete sexual maturation by the age of 18 years, in conjunction with low levels of circulating gonadotropins and testosterone and no other abnormalities of the hypothalamic-pituitary axis. HH24 is characterized by primary amenorrhea in women, oligo or azoospermia with low to normal testosterone levels in men, and infertility. The disease is caused by variants affecting the gene represented in this entry.

Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
FSHBCGABioGRID, DIP, HPRD, IntAct10563789 11222739 15662415 22802634 details
FSHBGPHA2IntAct12045258 details
FSHBFSHRDIP, HPRD, IntAct10395410 15662415 22802634 details
FSHBFSHBHPRD11222739 details
FSHBCGB3HPRD10563789 details