Entity Details
| Primary name |
PLSI_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q14651 |
| EntryName | PLSI_HUMAN |
| FullName | Plastin-1 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 629 |
| SequenceStatus | complete |
| DateCreated | 1997-11-01 |
| DateModified | 2021-06-02 |
Subcellular Location
Show/Hide Table
| Subcellular Location |
| Cell projection |
| Cytoplasm |
Domains
Show/Hide Table
| Domain | Name | Category | Type |
| IPR001589 | Actinin-type actin-binding domain, conserved site | Site | Conserved site |
| IPR001715 | Calponin homology domain | Domain | Domain |
| IPR002048 | EF-hand domain | Domain | Domain |
| IPR011992 | EF-hand domain pair | Family | Homologous superfamily |
| IPR018247 | EF-Hand 1, calcium-binding site | Site | Binding site |
| IPR030235 | Plastin-1 | Family | Family |
| IPR036872 | CH domain superfamily | Family | Homologous superfamily |
| IPR039959 | Fimbrin/Plastin | Family | Family |
Diseases
Show/Hide Table
| Disease ID | Source | Name | Description |
| 618787 | OMIM | Deafness, autosomal dominant, 76 (DFNA76) | A form of non-syndromic deafness characterized by mild to profound sensorineural hearing loss and variable age at onset. Sensorineural hearing loss results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. The disease is caused by variants affecting the gene represented in this entry. |
Interactions
1 interaction