Entity Details

Primary name EXOS7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15024
EntryNameEXOS7_HUMAN
FullNameExosome complex component RRP42
TaxID9606
Evidenceevidence at protein level
Length291
SequenceStatuscomplete
DateCreated2002-06-06
DateModified2021-06-02

Ontological Relatives

GenesEXOSC7

GO terms

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GOName
GO:0000175 3'-5'-exoribonuclease activity
GO:0000176 nuclear exosome (RNase complex)
GO:0000177 cytoplasmic exosome (RNase complex)
GO:0000178 exosome (RNase complex)
GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 RNA binding
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0006364 rRNA processing
GO:0006401 RNA catabolic process
GO:0016075 rRNA catabolic process
GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
GO:0034473 U1 snRNA 3'-end processing
GO:0034475 U4 snRNA 3'-end processing
GO:0034476 U5 snRNA 3'-end processing
GO:0043488 regulation of mRNA stability
GO:0043928 exonucleolytic catabolism of deadenylated mRNA
GO:0071028 nuclear mRNA surveillance
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic process
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic process
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001247 Exoribonuclease, phosphorolytic domain 1DomainDomain
IPR015847 Exoribonuclease, phosphorolytic domain 2DomainDomain
IPR020568 Ribosomal protein S5 domain 2-type foldFamilyHomologous superfamily
IPR027408 PNPase/RNase PH domain superfamilyFamilyHomologous superfamily
IPR036345 Exoribonuclease, PH domain 2 superfamilyFamilyHomologous superfamily

Diseases

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Interactions

28 interactions

InteractorPartnerSourcesPublicationsLink
EXOS7_HUMANEXOSX_HUMANBioGRID, HPRD, IntAct, UniProt11812149 15231747 21255825 24981860 26186194 26344197 28514442 29395067 details
EXOS7_HUMANDXO_HUMANBioGRID, HPRD, IntAct15231747 details
EXOS7_HUMANEXOS2_HUMANBioGRID, HPRD, IntAct, UniProt11719186 12419256 15231747 24981860 26186194 26344197 26496610 27173435 28514442 unassigned1312 details
EXOS7_HUMANEXOS4_HUMANBioGRID, HPRD, IntAct, MINT11719186 12419256 20531386 22939629 24981860 25416956 26186194 26344197 26496610 27173435 28514442 unassigned1312 details
EXOS7_HUMANEXOS1_HUMANBioGRID, DIP, HPRD, IntAct, UniProt11719186 11812149 12419256 12788944 24981860 25043052 26186194 26344197 26496610 28514442 details
EXOS7_HUMANMTMR3_HUMANIntAct12419256 details
EXOS7_HUMANIP6K1_HUMANBioGRID, HPRD, IntAct16189514 32296183 details
EXOS7_HUMANUB2Q1_HUMANIntAct19549727 details
EXOS7_HUMANUB2Q2_HUMANIntAct19549727 details
EXOS7_HUMANEXOS9_HUMANBioGRID, HPRD, IntAct, UniProt11719186 12788944 24981860 26186194 26344197 26496610 27173435 28514442 unassigned1312 details
EXOS7_HUMANUBE2K_HUMANBioGRID, IntAct32296183 details
EXOS7_HUMANERR3_HUMANBioGRID, IntAct32296183 details
EXOS7_HUMANHBS1L_HUMANBioGRID, IntAct26186194 27345150 28514442 details
EXOS7_HUMANMPH6_HUMANBioGRID, IntAct24981860 26186194 26344197 28514442 28877463 details
EXOS7_HUMANEXOS6_HUMANBioGRID, HPRD, IntAct11719186 12419256 15231747 22939629 24981860 26186194 28514442 details
EXOS7_HUMANA4_HUMANBioGRID21832049 details
EXOS7_HUMANPTEN_HUMANBioGRID31685992 details
EXOS7_HUMANRRP44_HUMANBioGRID, HPRD, MINT11719186 20531386 26344197 details
EXOS7_HUMANEXOS5_HUMANBioGRID, HPRD, IntAct, MINT11719186 24981860 26186194 26344197 26496610 28514442 details
EXOS7_HUMANDHYS_HUMANBioGRID, IntAct27173435 unassigned1312 details
EXOS7_HUMANLUM_HUMANBioGRID, IntAct27173435 unassigned1312 details
EXOS7_HUMANLRC47_HUMANBioGRID, IntAct27173435 unassigned1312 details
EXOS7_HUMANSLIT2_HUMANBioGRID, IntAct27173435 unassigned1312 details
EXOS7_HUMANRSRC1_HUMANBioGRID, IntAct27173435 unassigned1312 details
EXOS7_HUMANEXOS8_HUMANBioGRID, HPRD, IntAct11719186 24981860 26186194 28514442 details
EXOS7_HUMANMTREX_HUMANBioGRID, HPRD, IntAct11719186 24981860 26186194 28514442 details
EXOS7_HUMANZCCHV_HUMANDIP21876179 details
EXOS7_HUMANPALS2_HUMANHPRD11719186 details