Entity Details

Primary name GPIHBP1
Entity type gene
Source Source Link

Details

PrimaryID338328
RefseqGeneNG_034256
SymbolGPIHBP1
Nameglycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
Chromosome8
Location8q24.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2003-02-28
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsHDBP1_HUMAN

GO terms

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GOName
GO:0001523 retinoid metabolic process
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0006886 intracellular protein transport
GO:0008289 lipid binding
GO:0009897 external side of plasma membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0017038 protein import
GO:0031225 anchored component of membrane
GO:0031362 anchored component of external side of plasma membrane
GO:0034371 chylomicron remodeling
GO:0034394 protein localization to cell surface
GO:0035473 lipase binding
GO:0035478 chylomicron binding
GO:0042632 cholesterol homeostasis
GO:0045056 transcytosis
GO:0050821 protein stabilization
GO:0051004 regulation of lipoprotein lipase activity
GO:0051006 positive regulation of lipoprotein lipase activity
GO:0070328 triglyceride homeostasis
GO:0071503 response to heparin
GO:0071813 lipoprotein particle binding
GO:0090321 positive regulation of chylomicron remnant clearance
GO:0140318 protein transporter activity

Diseases

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Disease IDSourceNameDescription
615947 OMIMHyperlipoproteinemia 1D (HLPP1D)An autosomal recessive disorder characterized by hyperlipoproteinemia, decreased plasma LPL levels in some patients, high plasma triglyceride levels, and refractory fasting chylomicronemia. The disease is caused by variants affecting the gene represented in this entry.

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GPIHBP1LPLbhf-ucl, UniProt20124439 30559189 details