Entity Details

Primary name RSPO4
Entity type gene
Source Source Link

Details

PrimaryID343637
RefseqGeneNG_013043
SymbolRSPO4
NameR-spondin 4
Chromosome20
Location20p13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2003-03-28
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsRSPO4_HUMAN

GO terms

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GOName
GO:0005576 extracellular region
GO:0008201 heparin binding
GO:0016055 Wnt signaling pathway
GO:0030177 positive regulation of Wnt signaling pathway
GO:0035878 nail development

Diseases

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Disease IDSourceNameDescription
206800 OMIMNail disorder, non-syndromic congenital, 4 (NDNC4)A nail disorder characterized by congenital anonychia or its milder phenotypic variant hyponychia. Anonychia/hyponychia is the absence or severe hypoplasia of all fingernails and toenails without significant bone anomalies. The disease is caused by variants affecting the gene represented in this entry.

Interactions

15 interactions

InteractorPartnerSourcesPublicationsLink
RSPO4MAPK9BioGRID, IntAct32296183 details
RSPO4STK16BioGRID, IntAct32296183 details
RSPO4DHX57BioGRID, IntAct32296183 details
RSPO4HGSBioGRID, IntAct32296183 details
RSPO4PIH1D2BioGRID, IntAct32296183 details
RSPO4GUCD1BioGRID, IntAct32296183 details
RSPO4KLHL38BioGRID, IntAct32296183 details
RSPO4GNG13BioGRID, IntAct32296183 details
RSPO4MKRN3BioGRID, IntAct32296183 details
RSPO4ZNF330BioGRID, IntAct32296183 details
RSPO4GPSM3BioGRID, IntAct32296183 details
RSPO4ZNF77BioGRID, IntAct32296183 details
RSPO4LGR4BioGRID24050775 25504990 29752411 details
RSPO4USP20BioGRID32296183 details
RSPO4ANKRD11BioGRID32296183 details