Entity Details

Primary name IGFALS
Entity type gene
Source Source Link

Details

PrimaryID3483
RefseqGeneNG_011778
SymbolIGFALS
Nameinsulin like growth factor binding protein acid labile subunit
Chromosome16
Location16p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsALS_HUMAN

GO terms

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GOName
GO:0005520 insulin-like growth factor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0031012 extracellular matrix
GO:0042567 insulin-like growth factor ternary complex
GO:0044267 cellular protein metabolic process
GO:0070062 extracellular exosome

Diseases

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Disease IDSourceNameDescription
615961 OMIMAcid-labile subunit deficiency (ACLSD)A disorder characterized by severely reduced serum IGF-I and IGFBP-3 concentrations and mild growth retardation. Pubertal delay in boys and insulin insensitivity are common findings. The disease is caused by variants affecting the gene represented in this entry.

Interactions

6 interactions