Entity Details

Primary name PADI6
Entity type gene
Source Source Link

Details

PrimaryID353238
RefseqGeneNG_032943
SymbolPADI6
Namepeptidyl arginine deiminase 6
Chromosome1
Location1p36.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2003-05-22
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPADI6_HUMAN

GO terms

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GOName
GO:0004668 protein-arginine deiminase activity
GO:0005509 calcium ion binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0007010 cytoskeleton organization
GO:0007028 cytoplasm organization
GO:0030133 transport vesicle
GO:0036414 histone citrullination
GO:0040016 embryonic cleavage
GO:0043143 regulation of translation by machinery localization
GO:0045111 intermediate filament cytoskeleton
GO:0060473 cortical granule

Diseases

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Disease IDSourceNameDescription
617234 OMIMPreimplantation embryonic lethality 2 (PREMBL2)A rare cause of female primary infertility. In affected women, ovulation and fertilization proceed normally but embryos are arrested at early stages of development. Inheritance is autosomal recessive. The disease is caused by variants affecting the gene represented in this entry.

Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
PADI6ZNF526BioGRID, IntAct32296183 details
PADI6DDIT4LIntAct32296183 details
PADI6SUV39H1BioGRID, IntAct32296183 details
PADI6KLHL2BioGRID, IntAct32296183 details
PADI6MTA3IntAct26028330 details