Entity Details

Primary name IL11RA
Entity type gene
Source Source Link

Details

PrimaryID3590
RefseqGeneNG_028966
SymbolIL11RA
Nameinterleukin 11 receptor subunit alpha
Chromosome9
Location9p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1996-06-19
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsI11RA_HUMAN

GO terms

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GOName
GO:0004888 transmembrane signaling receptor activity
GO:0004896 cytokine receptor activity
GO:0004921 interleukin-11 receptor activity
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0008284 positive regulation of cell population proliferation
GO:0009897 external side of plasma membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0019955 cytokine binding
GO:0019970 interleukin-11 binding
GO:0032502 developmental process
GO:0043235 receptor complex
GO:0060322 head development

Diseases

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Disease IDSourceNameDescription
614188 OMIMCraniosynostosis and dental anomalies (CRSDA)A disorder characterized by craniosynostosis, maxillary hypoplasia, and dental anomalies, including malocclusion, delayed and ectopic tooth eruption, and/or supernumerary teeth. Some patients also display minor digit anomalies, such as syndactyly and/or clinodactyly. The disease is caused by variants affecting the gene represented in this entry.

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
IL11RAOLFM4BioGRID, IntAct32296183 details
IL11RAIL11IntAct26551460 details