Entity Details

Primary name ITGA2
Entity type gene
Source Source Link

Details

PrimaryID3673
RefseqGeneNG_008330
SymbolITGA2
Nameintegrin subunit alpha 2
Chromosome5
Location5q11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-02-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsITA2_HUMAN

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0001618 virus receptor activity
GO:0001666 response to hypoxia
GO:0002687 positive regulation of leukocyte migration
GO:0005178 integrin binding
GO:0005518 collagen binding
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006929 substrate-dependent cell migration
GO:0006971 hypotonic response
GO:0007155 cell adhesion
GO:0007160 cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0007565 female pregnancy
GO:0007596 blood coagulation
GO:0008283 cell population proliferation
GO:0008305 integrin complex
GO:0009887 animal organ morphogenesis
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010634 positive regulation of epithelial cell migration
GO:0010694 positive regulation of alkaline phosphatase activity
GO:0014075 response to amine
GO:0014850 response to muscle activity
GO:0014911 positive regulation of smooth muscle cell migration
GO:0030198 extracellular matrix organization
GO:0030879 mammary gland development
GO:0031346 positive regulation of cell projection organization
GO:0031589 cell-substrate adhesion
GO:0032967 positive regulation of collagen biosynthetic process
GO:0033343 positive regulation of collagen binding
GO:0033591 response to L-ascorbic acid
GO:0033627 cell adhesion mediated by integrin
GO:0034666 integrin alpha2-beta1 complex
GO:0038064 collagen receptor activity
GO:0038065 collagen-activated signaling pathway
GO:0042493 response to drug
GO:0043236 laminin binding
GO:0043388 positive regulation of DNA binding
GO:0043395 heparan sulfate proteoglycan binding
GO:0043589 skin morphogenesis
GO:0043679 axon terminus
GO:0044877 protein-containing complex binding
GO:0045178 basal part of cell
GO:0045184 establishment of protein localization
GO:0045727 positive regulation of translation
GO:0045785 positive regulation of cell adhesion
GO:0045987 positive regulation of smooth muscle contraction
GO:0046872 metal ion binding
GO:0048041 focal adhesion assembly
GO:0048333 mesodermal cell differentiation
GO:0048471 perinuclear region of cytoplasm
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0050729 positive regulation of inflammatory response
GO:0050927 positive regulation of positive chemotaxis
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
GO:0051971 positive regulation of transmission of nerve impulse
GO:0060100 positive regulation of phagocytosis, engulfment
GO:0070365 hepatocyte differentiation
GO:0071107 response to parathyroid hormone
GO:0071260 cellular response to mechanical stimulus
GO:0071392 cellular response to estradiol stimulus
GO:0098639 collagen binding involved in cell-matrix adhesion

Diseases

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Interactions

63 interactions

InteractorPartnerSourcesPublicationsLink
ITGA2ITGA2HPRD, IntAct14681217 details
ITGA2ITGB1BioGRID, IntAct, matrixdb10397731 14681217 21947080 details
ITGA2PDIA3BioGRID, MINT17170699 details
ITGA2COL1A2HPRD, MINT17485091 2156854 details
ITGA2FABP3I2D20802519 details
ITGA2SHARPINBioGRID, IntAct21947080 28775156 details
ITGA2AUP1BioGRID12042322 details
ITGA2MMP1BioGRID, HPRD11359774 11359786 details
ITGA2LAMA1BioGRID, HPRD9688542 details
ITGA2RABIFBioGRID10094488 details
ITGA2TSC22D2BioGRID27337956 details
ITGA2APPBioGRID27221710 details
ITGA2WASLMINT16582881 details
ITGA2CIB1MINT16582881 details
ITGA2KDRmatrixdb21596751 details
ITGA2CD9HPRD, UniProt26686862 9812906 9813091 details
ITGA2ACE2IntAct22523556 details
ITGA2COL1A1BioGRID, HPRD11359786 11856343 2156854 details
ITGA2CD46BioGRID10741407 details
ITGA2PSMD4BioGRID16762342 details
ITGA2VHLBioGRID18523483 details
ITGA2CA9BioGRID28692057 details
ITGA2EGFRBioGRID31641961 details
ITGA2HSPG2HPRD15240572 details
ITGA2ACTA1HPRD7503723 details
ITGA2COL8A1HPRD10666376 12482545 details
ITGA2ALBBioGRID, IntAct15174051 details
ITGA2ATF2BioGRID, IntAct22304920 details
ITGA2RSRP1BioGRID, IntAct26496610 details
ITGA2MGAT4CBioGRID, IntAct28514442 details
ITGA2LGALS8BioGRID, IntAct26186194 28514442 details
ITGA2SCGB1D1BioGRID, IntAct28514442 details
ITGA2BTNL8BioGRID, IntAct26186194 28514442 details
ITGA2TMED6BioGRID, IntAct28514442 details
ITGA2LGALS3BioGRID, IntAct26186194 28514442 details
ITGA2SERPINA12BioGRID, IntAct28514442 details
ITGA2ZACNBioGRID, IntAct26186194 28514442 details
ITGA2CD47matrixdb10397731 details
ITGA2LAMP1BioGRID, IntAct29568061 34079125 details
ITGA2TSPAN5UniProt26686862 details
ITGA2TSPAN15UniProt26686862 details
ITGA2TSPAN14UniProt26686862 details
ITGA2SH3BGRLBioGRID, IntAct31980649 details
ITGA2RAB5ABioGRID, IntAct31980649 details
ITGA2ERGIC1BioGRID22939629 details
ITGA2CFTRBioGRID26618866 details
ITGA2RNF4BioGRID29180619 details
ITGA2HRASBioGRID30639242 details
ITGA2KRASBioGRID30639242 34079125 details
ITGA2OTULINLBioGRID31056421 details
ITGA2ARF6BioGRID34079125 details
ITGA2CAV1BioGRID34079125 details
ITGA2DIRAS3BioGRID34079125 details
ITGA2GJD3BioGRID34079125 details
ITGA2LAMP3BioGRID34079125 details
ITGA2LAMTOR1BioGRID34079125 details
ITGA2LYNBioGRID34079125 details
ITGA2MARCKSBioGRID34079125 details
ITGA2RAB11ABioGRID34079125 details
ITGA2RAB2ABioGRID34079125 details
ITGA2RAB35BioGRID34079125 details
ITGA2RHOBBioGRID34079125 details
ITGA2VIRMABioGRID29507755 details