Entity Details

Primary name MGMT
Entity type gene
Source Source Link

Details

PrimaryID4255
RefseqGeneNG_052673
SymbolMGMT
NameO-6-methylguanine-DNA methyltransferase
Chromosome10
Location10q26.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1991-06-07
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsMGMT_HUMAN

GO terms

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GOName
GO:0003677 DNA binding
GO:0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006266 DNA ligation
GO:0006281 DNA repair
GO:0006307 DNA dealkylation involved in DNA repair
GO:0008168 methyltransferase activity
GO:0009008 DNA-methyltransferase activity
GO:0016020 membrane
GO:0043066 negative regulation of apoptotic process
GO:0046872 metal ion binding
GO:2000781 positive regulation of double-strand break repair

Diseases

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Interactions

80 interactions

InteractorPartnerSourcesPublicationsLink
MGMTCSNK2A1BioGRID, HPRD10667577 details
MGMTCSNK2A2BioGRID10667577 details
MGMTPRKACABioGRID, HPRD10667577 details
MGMTPRKCABioGRID, HPRD10667577 12430183 details
MGMTESR1BioGRID11564893 details
MGMTPCNABioGRID16226712 29510343 details
MGMTCREBBPBioGRID, HPRD11564893 details
MGMTEP300BioGRID, HPRD11564893 details
MGMTSMC1ABioGRID16226712 details
MGMTH4C1BioGRID16226712 details
MGMTH2AC17BioGRID16226712 details
MGMTH2BW2BioGRID16226712 details
MGMTH3-4BioGRID16226712 details
MGMTMCM3BioGRID16226712 details
MGMTMSH2BioGRID16226712 details
MGMTTOP1BioGRID16226712 details
MGMTPRKDCBioGRID16226712 details
MGMTXRCC6BioGRID16226712 details
MGMTDDX5BioGRID16226712 details
MGMTDDX24BioGRID16226712 details
MGMTUSP19BioGRID16226712 details
MGMTRNF8BioGRID16226712 details
MGMTPSME2BioGRID16226712 details
MGMTUBBBioGRID16226712 details
MGMTPSMD9BioGRID16226712 details
MGMTFBXO2BioGRID16226712 details
MGMTFBXO27BioGRID16226712 details
MGMTHSP90AA1BioGRID16226712 details
MGMTHSP90AB1BioGRID16226712 details
MGMTCDK12BioGRID16226712 details
MGMTCDK10BioGRID16226712 details
MGMTPRKCHBioGRID16226712 details
MGMTPRPF4BioGRID16226712 details
MGMTCDKL5BioGRID16226712 details
MGMTSETBioGRID16226712 details
MGMTPTPN4BioGRID16226712 details
MGMTYWHAZBioGRID16226712 details
MGMTKPNB1BioGRID16226712 details
MGMTWNT9BBioGRID16226712 details
MGMTPABPC3BioGRID16226712 details
MGMTANP32EBioGRID16226712 details
MGMTNCLBioGRID16226712 details
MGMTHNRNPA2B1BioGRID16226712 details
MGMTHNRNPCBioGRID16226712 details
MGMTRPS15ABioGRID16226712 details
MGMTRPLP1BioGRID16226712 details
MGMTEIF3HBioGRID16226712 details
MGMTEEF1A1BioGRID16226712 details
MGMTEEF1A2BioGRID16226712 details
MGMTEEF1B2BioGRID16226712 details
MGMTSLC25A4BioGRID16226712 details
MGMTSLC25A6BioGRID16226712 details
MGMTPKMBioGRID16226712 details
MGMTTTPABioGRID16226712 details
MGMTIL25BioGRID16226712 details
MGMTFBLBioGRID16226712 details
MGMTTUBB4BBioGRID16226712 details
MGMTTUBA1CBioGRID16226712 details
MGMTANXA1BioGRID16226712 details
MGMTANXA2BioGRID16226712 details
MGMTACTBBioGRID16226712 details
MGMTMYO7ABioGRID16226712 details
MGMTVIMBioGRID16226712 details
MGMTPHBBioGRID16226712 details
MGMTSRP9BioGRID16226712 details
MGMTSSRP1BioGRID16226712 details
MGMTCDK2BioGRID16226712 29510343 details
MGMTCDK1BioGRID16226712 details
MGMTCCNB1BioGRID16226712 details
MGMTCDKN1ABioGRID16226712 29510343 details
MGMTMCM2BioGRID16226712 details
MGMTORC1BioGRID16226712 details
MGMTPOLD1BioGRID16226712 details
MGMTBRCA2BioGRID19047179 details
MGMTDTLBioGRID29510343 details
MGMTUBA1HPRD8573590 details
MGMTFANCABioGRID28215707 details
MGMTESR2BioGRID29509190 details
MGMTVCPBioGRID29540532 details
MGMTPLEKHA4BioGRID31091453 details