Entity Details

Primary name MMP8
Entity type gene
Source Source Link

Details

PrimaryID4317
RefseqGeneNG_012101
SymbolMMP8
Namematrix metallopeptidase 8
Chromosome11
Location11q22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-03-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsMMP8_HUMAN

GO terms

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GOName
GO:0004175 endopeptidase activity
GO:0004222 metalloendopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006508 proteolysis
GO:0008233 peptidase activity
GO:0008270 zinc ion binding
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0022617 extracellular matrix disassembly
GO:0030198 extracellular matrix organization
GO:0030574 collagen catabolic process
GO:0032693 negative regulation of interleukin-10 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0035580 specific granule lumen
GO:0035987 endodermal cell differentiation
GO:0043312 neutrophil degranulation
GO:0043388 positive regulation of DNA binding
GO:0043410 positive regulation of MAPK cascade
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0046330 positive regulation of JNK cascade
GO:0062023 collagen-containing extracellular matrix
GO:0150077 regulation of neuroinflammatory response
GO:0150078 positive regulation of neuroinflammatory response
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1903428 positive regulation of reactive oxygen species biosynthetic process
GO:1903978 regulation of microglial cell activation
GO:1903980 positive regulation of microglial cell activation
GO:1904724 tertiary granule lumen

Diseases

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Interactions

7 interactions