Entity Details

Primary name MOG
Entity type gene
Source Source Link

Details

PrimaryID4340
RefseqGeneNG_031873
SymbolMOG
Namemyelin oligodendrocyte glycoprotein
Chromosome6
Location6p22.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsMOG_HUMAN

GO terms

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GOName
GO:0001618 virus receptor activity
GO:0001817 regulation of cytokine production
GO:0005102 signaling receptor binding
GO:0005886 plasma membrane
GO:0007155 cell adhesion
GO:0007417 central nervous system development
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0050852 T cell receptor signaling pathway

Diseases

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Disease IDSourceNameDescription
614250 OMIMNarcolepsy 7 (NRCLP7)Neurological disabling sleep disorder, characterized by excessive daytime sleepiness, sleep fragmentation, symptoms of abnormal rapid-eye-movement (REM) sleep, cataplexy, hypnagogic hallucinations, and sleep paralysis. Cataplexy is a sudden loss of muscle tone triggered by emotions, which is the most valuable clinical feature used to diagnose narcolepsy. Human narcolepsy is primarily a sporadically occurring disorder but familial clustering has been observed. The disease is caused by variants affecting the gene represented in this entry.

Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
MOGADRB2BioGRID, MINT28298427 details
MOGTSHRBioGRID, MINT28298427 details
MOGHTTIntAct32814053 details
MOGPRNPHPRD15146195 details
MOGOTUD4BioGRID, IntAct19615732 details
MOGTRIM37BioGRID33194618 details