Entity Details

Primary name PLA2G3
Entity type gene
Source Source Link

Details

PrimaryID50487
RefseqGene
SymbolPLA2G3
Namephospholipase A2 group III
Chromosome22
Location22q12.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-03-23
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPA2G3_HUMAN

GO terms

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GOName
GO:0001675 acrosome assembly
GO:0002532 production of molecular mediator involved in inflammatory response
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005814 centriole
GO:0005886 plasma membrane
GO:0006644 phospholipid metabolic process
GO:0006658 phosphatidylserine metabolic process
GO:0007288 sperm axoneme assembly
GO:0010629 negative regulation of gene expression
GO:0010744 positive regulation of macrophage derived foam cell differentiation
GO:0010976 positive regulation of neuron projection development
GO:0019372 lipoxygenase pathway
GO:0031394 positive regulation of prostaglandin biosynthetic process
GO:0032308 positive regulation of prostaglandin secretion
GO:0034374 low-density lipoprotein particle remodeling
GO:0034375 high-density lipoprotein particle remodeling
GO:0036148 phosphatidylglycerol acyl-chain remodeling
GO:0036151 phosphatidylcholine acyl-chain remodeling
GO:0036152 phosphatidylethanolamine acyl-chain remodeling
GO:0042116 macrophage activation
GO:0043303 mast cell degranulation
GO:0043524 negative regulation of neuron apoptotic process
GO:0046337 phosphatidylethanolamine metabolic process
GO:0046470 phosphatidylcholine metabolic process
GO:0046471 phosphatidylglycerol metabolic process
GO:0046473 phosphatidic acid metabolic process
GO:0046488 phosphatidylinositol metabolic process
GO:0046872 metal ion binding
GO:0047498 calcium-dependent phospholipase A2 activity
GO:0048469 cell maturation
GO:0050482 arachidonic acid secretion
GO:0055037 recycling endosome
GO:0060271 cilium assembly
GO:0060376 positive regulation of mast cell differentiation
GO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
GO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
GO:1900017 positive regulation of cytokine production involved in inflammatory response
GO:1900222 negative regulation of amyloid-beta clearance
GO:1903595 positive regulation of histamine secretion by mast cell
GO:2001135 regulation of endocytic recycling

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PLA2G3PVRBioGRID, IntAct21988832 details
PLA2G3TGFB1I1BioGRID, IntAct21988832 details