Entity Details

Primary name TNNI3K
Entity type gene
Source Source Link

Details

PrimaryID51086
RefseqGeneNG_032939
SymbolTNNI3K
NameTNNI3 interacting kinase
Chromosome1
Location1p31.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-11
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTNI3K_HUMAN

GO terms

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GOName
GO:0002027 regulation of heart rate
GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006468 protein phosphorylation
GO:0008022 protein C-terminus binding
GO:0031013 troponin I binding
GO:0046872 metal ion binding
GO:0055117 regulation of cardiac muscle contraction
GO:0086069 bundle of His cell to Purkinje myocyte communication
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1903779 regulation of cardiac conduction

Diseases

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Disease IDSourceNameDescription
616117 OMIMCardiac conduction disease with or without dilated cardiomyopathy (CCDD)A cardiac disorder characterized by atrial tachyarrhythmia and conduction system disease. Some patients have dilated cardiomyopathy. The disease is caused by variants affecting the gene represented in this entry.

Interactions

10 interactions

InteractorPartnerSourcesPublicationsLink
TNNI3KTNNI3BioGRID, IntAct12721663 23369981 details
TNNI3KACTC1BioGRID, IntAct12721663 details
TNNI3KACTA1BioGRID, IntAct12721663 details
TNNI3KMYBPC3BioGRID, IntAct12721663 details
TNNI3KAIPBioGRID, IntAct12721663 details
TNNI3KFABP3BioGRID, IntAct12721663 details
TNNI3KHADHBBioGRID, IntAct12721663 details
TNNI3KFBXO4BioGRID, IntAct32296183 details
TNNI3KHSP90AA1BioGRID22939624 details
TNNI3KECT2BioGRID31586073 details