Entity Details

Primary name PIGC
Entity type gene
Source Source Link

Details

PrimaryID5279
RefseqGeneNG_050631
SymbolPIGC
Namephosphatidylinositol glycan anchor biosynthesis class C
Chromosome1
Location1q24.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1997-10-16
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPIGC_HUMAN

GO terms

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GOName
GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO:0003824 catalytic activity
GO:0005789 endoplasmic reticulum membrane
GO:0006506 GPI anchor biosynthetic process
GO:0016021 integral component of membrane
GO:0016254 preassembly of GPI anchor in ER membrane
GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity

Diseases

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Disease IDSourceNameDescription
617816 OMIMGlycosylphosphatidylinositol biosynthesis defect 16 (GPIBD16)An autosomal recessive disorder characterized by delayed psychomotor development, intellectual disability, and seizures. The disease is caused by variants affecting the gene represented in this entry.

Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
PIGCZHX1BioGRID, HPRD, IntAct16169070 details
PIGCKLF10BioGRID, MINT21900206 details
PIGCPIGQBioGRID, HPRD, UniProt9463366 details
PIGCDPM2HPRD10944123 details
PIGCPIGHUniProt9463366 details
PIGCPIGAUniProt16162815 9463366 details