Entity Details

Primary name RIN2
Entity type gene
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Details

PrimaryID54453
RefseqGeneNG_016310
SymbolRIN2
NameRas and Rab interactor 2
Chromosome20
Location20p11.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-06-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsRIN2_HUMAN

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005829 cytosol
GO:0006897 endocytosis
GO:0007264 small GTPase mediated signal transduction
GO:0010595 positive regulation of endothelial cell migration
GO:0030695 GTPase regulator activity
GO:0043547 positive regulation of GTPase activity
GO:1904906 positive regulation of endothelial cell-matrix adhesion via fibronectin
GO:2001214 positive regulation of vasculogenesis

Diseases

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Disease IDSourceNameDescription
613075 OMIMMACS syndrome (MACS)A complex disorder of elastic tissue characterized by sagging skin and occasionally by life-threatening visceral complications. The disease is caused by variants affecting the gene represented in this entry.