Entity Details

Primary name POU4F3
Entity type gene
Source Source Link

Details

PrimaryID5459
RefseqGeneNG_011885
SymbolPOU4F3
NamePOU class 4 homeobox 3
Chromosome5
Location5q32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPO4F3_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007601 visual perception
GO:0007605 sensory perception of sound
GO:0021562 vestibulocochlear nerve development
GO:0031290 retinal ganglion cell axon guidance
GO:0042472 inner ear morphogenesis
GO:0042491 inner ear auditory receptor cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048675 axon extension
GO:0050885 neuromuscular process controlling balance
GO:0051402 neuron apoptotic process
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Disease IDSourceNameDescription
602459 OMIMDeafness, autosomal dominant, 15 (DFNA15)A form of non-syndromic hearing loss with variable phenotype in terms of age at onset, levels of progression, and shape of audiograms. The disease is caused by variants affecting the gene represented in this entry.

Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
POU4F3GOLGA2BioGRID, IntAct32296183 details
POU4F3KRT31BioGRID, IntAct32296183 details
POU4F3PLA2G10BioGRID, IntAct32296183 details
POU4F3NHLRC4BioGRID, IntAct32296183 details
POU4F3DUSP21BioGRID, IntAct32296183 details
POU4F3AURKABioGRID28218735 details