Entity Details

Primary name CNGB3
Entity type gene
Source Source Link

Details

PrimaryID54714
RefseqGeneNG_016980
SymbolCNGB3
Namecyclic nucleotide gated channel subunit beta 3
Chromosome8
Location8q21.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-07-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCNGB3_HUMAN

GO terms

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GOName
GO:0001750 photoreceptor outer segment
GO:0005222 intracellular cAMP-activated cation channel activity
GO:0005223 intracellular cGMP-activated cation channel activity
GO:0006812 cation transport
GO:0007165 signal transduction
GO:0007601 visual perception
GO:0030553 cGMP binding
GO:1902495 transmembrane transporter complex

Diseases

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Disease IDSourceNameDescription
248200 OMIMStargardt disease 1 (STGD1)A common hereditary macular degeneration. It is characterized by decreased central vision, atrophy of the macula and underlying retinal pigment epithelium, and frequent presence of prominent flecks in the posterior pole of the retina. The disease is caused by variants affecting the gene represented in this entry.
262300 OMIMAchromatopsia 3 (ACHM3)An autosomal recessive, ocular stationary disorder due to the absence of functioning cone photoreceptors in the retina. It is characterized by total colorblindness, low visual acuity, photophobia and nystagmus. Achromatopsia type 3 patients manifest severe myopia. The disease is caused by variants affecting the gene represented in this entry.

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
CNGB3CNGA3BioGRID15223812 details
CNGB3NEK4BioGRID, MINT25798074 details
CNGB3APBB1UniProt24284412 details
CNGB3RNF208BioGRID31862882 details