Entity Details

Primary name BNC2
Entity type gene
Source Source Link

Details

PrimaryID54796
RefseqGeneNG_051226
SymbolBNC2
Namebasonuclin 2
Chromosome9
Location9p22.3-p22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-07-03
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsBNC2_HUMAN

GO terms

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GOName
GO:0000976 transcription cis-regulatory region binding
GO:0003416 endochondral bone growth
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0043586 tongue development
GO:0046872 metal ion binding
GO:0060021 roof of mouth development
GO:0060485 mesenchyme development

Diseases

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Disease IDSourceNameDescription
618612 OMIMLower urinary tract obstruction, congenital (LUTO)A disorder characterized by urinary bladder outflow obstruction, which can represent an anatomical blockage or a functional obstruction. The most common anatomical causes are posterior urethral valves at the level of the prostatic urethra, a lesion unique to males. Less common are anterior urethral valves, also called urethral atresia, that can occur in either sex. LUTO is an autosomal dominant disease with variable expression. The disease is caused by variants affecting the gene represented in this entry.

Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
BNC2LMO1BioGRID, IntAct32296183 details
BNC2RB1HPRD15949438 details
BNC2IRF6BioGRID, IntAct21903422 details
BNC2CHCHD10BioGRID, IntAct28514442 details
BNC2ZDHHC5UniProt31402609 details
BNC2BRCA2BioGRID27433848 details
BNC2TP53BioGRID32807901 details
BNC2VIRMABioGRID29507755 details